Naltrexone Therapy and Relapse Rates of Opioid Dependent Individuals

F Tatary; J Shakeri; A Nasiri; L Ghelichi; Gh  Abdoli

Journal of Kermanshah University of Medical Sciences

Peer-reviewed Medical Quarterly

Home

Instructions

Authors Guide Submit Manuscript

Outlines

Abstract
Copyright

Naltrexone Therapy and Relapse Rates of Opioid Dependent Individuals

Author(s):

F Tatary^1,*,

J Shakeri¹,

A Nasiri¹,

L Ghelichi¹,

Gh Abdoli¹

1Iran

Journal of Kermanshah University of Medical Sciences:Vol. 10, issue 4; e81827

Published online:Mar 19, 2007

Article type:Research Article

Received:Jun 27, 2005

Accepted:May 30, 2006

How to Cite:Tatary F, Shakeri J, Nasiri A, Ghelichi L, Abdoli G. Naltrexone Therapy and Relapse Rates of Opioid Dependent Individuals. J Kermanshah Univ Med Sci. 2007;10(4):e81827. doi:

Abstract

Introduction: Drug addiction and drug dependency are major problem in the “mental”,”social”, and “health-care” fields. It decreases occupational performance and educational abilities in different social groups, and may lead to miscellaneous crimes. Different methods are recommended for drug addiction treatments. Detoxification is the first step however it would not be successful without follow up and vigorous maintenance therapy. Naltrexone introduced as an opium antagonist to decrease desire for opiates and is used for maintenance therapy of drug treatments in Kermanshah Rehabilitation and Therapy Center since 2001. This study aimed to determine the relapse rates of drug addict patients under maintenance therapy by Naltrexone after 18 months follow up.

Materials & Methods: 150 drug addicts who were admitted in Kermanshah Rehabilitation and Therapy Center were recruited flowing detoxification period. They received Naltrexone maintenance therapy for six months and followed for 12 months to find out their drug addiction relapse. Opium test (T.L.C) were measured monthly during six months and followed with three-month intervals for next 12 months.

Results: Relapse rate in the maintenance therapy period were 56.7% and 4.7% respectively. The achievement rate was 38.7%. Socio-demographic findings showed that relapse rate were highest in young adults (18-25 years old) and lowest in employed subject. According to the drug type, consumption method and interval; heroin users, drug inhalation and 2-3 times daily users showed more achievements than other drug addicts.

Conclusion: We conclude that the first nine months after detoxification is more critical period, Naltrexone maintenance therapy, helps to long lasting give up drug addiction. The employees and subjects with well social discipline and educational background have more chance to stop opium abuse.

Keywords

Treatment of Addiction

Naltrexone

Kermanshah Rehabilitation and Therapy Center - Relapse

Fulltext

The full text of this article is available on PDF

Six-Month Follow-Up Study of Ultrarapid Opiate Detoxification With Naltrexone

Mohammad Forozeshfard,

Babak Hosseinzadeh Zoroufchi,

Mohammad Bagher Saberi Zafarghandi,

Razieh Bandari,

Behzad Foroutan

Forozeshfard M, Hosseinzadeh Zoroufchi B, Saberi Zafarghandi MB, Bandari R, Foroutan B. Six-Month Follow-Up Study of Ultrarapid Opiate Detoxification With Naltrexone. Int J High Risk Behav Addict. 2014;3(4):e20944. doi: https://doi.org/10.5812/ijhrba.20944

1

Sep

2015

Survival Analysis of Drug Abuse Relapse in Addiction Treatment Centers

Aziz Kassani,

Mohsen Niazi,

Jafar Hassanzadeh,

Rostam Menati

Kassani A, Niazi M, Hassanzadeh J, Menati R. Survival Analysis of Drug Abuse Relapse in Addiction Treatment Centers. Int J High Risk Behav Addict. 2015;4(3):e23402. doi: https://doi.org/10.5812/ijhrba.23402

6

Mar

2013

Demographic Features of Patients on Methadone Maintenance Treatment in Zahedan, Iran

Saeede Olyaee,

Raheleh Rafaiee

Olyaee S, Rafaiee R. Demographic Features of Patients on Methadone Maintenance Treatment in Zahedan, Iran. Zahedan J Res Med Sci. 2014;16(9):. doi:

22

Apr

2012

Demographic Features of Patients in Methadone Maintenance Treatment, Referred To Private Mmt Clinic, Sari-Iran (2009-2010)

Seyyed Hamzeh Hosseini,

Mehrdad Taghipour,

Mehrdad Tavakkoli,

Amir Hamta

Hosseini SH, Taghipour M, Tavakkoli M, Hamta A. Demographic Features of Patients in Methadone Maintenance Treatment, Referred To Private Mmt Clinic, Sari-Iran (2009-2010). Shiraz E-Med J. 2012;13(3):. doi:

30

Jun

2012

Nonmedical Abuse of Benzodiazepines in Opiate-Dependent Patients in Tehran, Iran

Masuade Babakhanian,

Maliheh Sadeghi,

Nader Mansoori,

Zahra Alam Mehrjerdi,

Mahmood Tabataba1

Babakhanian M, Sadeghi M, Mansoori N, Alam Mehrjerdi Z, Tabataba1 M. Nonmedical Abuse of Benzodiazepines in Opiate-Dependent Patients in Tehran, Iran. Iran J Psychiatry Behav Sci. 2012;6(1):. doi:

Import into EndNote Import into BibTex

Share on

Comments

Number of Comments:0

Cited by

Scopus by DOI: 0
Last Update: 2 weeks ago
Scopus by Title: 0
Last Update: 2 weeks ago
Scopus by Title (Ref): 3
Last Update: 2 weeks ago
CrossRef: 0
Last Update: 1 day ago

Metrics

Ordering Reprints

Articles are published under the Creative Commons license stated on each article. No permission or royalty fee is required for uses permitted by that license. CCC handles optional bulk and customized reprint orders. Any quotation covers production and delivery services only, not copyright permission. > Request Reprints from CCC

Search Relations

Author(s):

F Tatary:[PubMed][Scholar]
J Shakeri:[PubMed][Scholar]
A Nasiri:[PubMed][Scholar]
L Ghelichi:[PubMed][Scholar]
Gh Abdoli:[PubMed][Scholar]

Peer-reviewed Medical Quarterly

Outlines

Naltrexone Therapy and Relapse Rates of Opioid Dependent Individuals

Abstract

Fulltext

Similar Articles

Six-Month Follow-Up Study of Ultrarapid Opiate Detoxification With Naltrexone

Survival Analysis of Drug Abuse Relapse in Addiction Treatment Centers

Demographic Features of Patients on Methadone Maintenance Treatment in Zahedan, Iran

Demographic Features of Patients in Methadone Maintenance Treatment, Referred To Private Mmt Clinic, Sari-Iran (2009-2010)

Nonmedical Abuse of Benzodiazepines in Opiate-Dependent Patients in Tehran, Iran

Last Update: 2 weeks ago

Last Update: 2 weeks ago

Last Update: 2 weeks ago

Last Update: 1 day ago