Development and Evaluation of Talisapatradi and Vyoshadi Choorna Lozenges: An Ayurvedic Traditional Formulation
Authors
Abstract
In Ayurveda, Talisapatradi choorna (TPC) and Vyoshadi choorna (VSC) are commonly used medicines for
cough, cold, asthma, and rhinitis. These symptoms are due to upper respiratory infections of predominantly
of viral origin. Currently, there are no effective medicines except indiscriminate uses of antibiotics, local
anesthetics, and pain killers. The conventional formulation of TPC and VSC is difficult to administer
so an easy manufacturing lozenge formulation was developed. The phytochemical analysis was done
by preliminary thin layer chromatography (TLC) derivatization studies. High-performance thin layer
chromatography (HPTLC) analysis confirmed the presence of herbal actives in the lozenge formulations.
The TLC analysis results showed that TPC and VSC contain phytochemicals of flavonoids, steroids and
phytosterols, and alkaloids family. The herbal actives were found to be stable in the final formulation
without any interference with the excipients used in the formulation. The lozenges formulated from TPC
and VSC are found to be promising alternatives to traditional form for the traditional Ayurvedic preparation.
Compatibility study was done using Fourier transform infrared spectroscopy and HPTLC study.
Highlights
Copyright
© 2022, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.
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