Koomesh
Journal of Semnan University of Medical Sciences
Antibiotic resistance profile and capsular serotyping of Streptococcus agalactiae isolated from pregnant women between 35 to 37 weeks of pregnancy
Abstract
Introduction: Streptococcus agalactiae (streptococcus group B (GBS)) is the natural inhabitants of the gastrointestinal and genitourinary tract and frequently is isolated from female reproductive tract. It is the most common cause of bacterial sepsis, meningitis, pneumonia and severe diseases in the newborn. Materials and Methods: Sixty Streptococcus agalactiae isolates were collected from 500 vaginal smear samples from pregnant women in their 35 to 37 weeks of pregnancy. The antibiotic susceptibility testing was performed by using disk diffusion method on Mueller Hinton agar medium with 5% sheep blood followed by capsular serotyping and PCR for 16Sr RNA, for final approval. Results: Antibiotic susceptibility test showed the lowest resistance was belong to Penicillin, ampicillin, vancomycin (0%), cefazolin (3/33%) and ceftazidime (5%).While the highest resistance was found for erythromycin (28/33%), clindamycin (15%) and tetracycline (96/66%) antibiotics. The frequency of capsular serotypes was as following: III=45%, Ia=18/33%, II=16/66%, V=13/33% and Ib=5%. Conclusion: Based on the current study, high raise in GBS isolates resistance to erythromycin and clindamycin in pregnant women (within the 35-37th weeks of pregnancy) is alarming and Markazi province demands for an expanded screening program in the ground of their GBS preventative plan.
Copyright
© 2016, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.
Similar Articles
Frequency of Antibiotic Resistance and Virulence Factors in Streptococcus agalactiae Isolated from Vaginal and Urine Samples of Pregnant Women in Yazd, Iran: A Cross-sectional Study
Azartoos N, Sadeh M, Vakili M. Frequency of Antibiotic Resistance and Virulence Factors in Streptococcus agalactiae Isolated from Vaginal and Urine Samples of Pregnant Women in Yazd, Iran: A Cross-sectional Study. Jundishapur J Microbiol. 2025;18(10):e162606. doi: https://doi.org/10.5812/jjm-162606
Molecular Characterization of Streptococcus agalactiae Isolates From Pregnant and Non-Pregnant Women at Yazd University Hospital, Iran
Sadeh M, Firouzi R, Derakhshandeh A, Bagher Khalili M, Kong F, et al. Molecular Characterization of Streptococcus agalactiae Isolates From Pregnant and Non-Pregnant Women at Yazd University Hospital, Iran. Jundishapur J Microbiol. 2016;9(2):e30412. doi: https://doi.org/10.5812/jjm.30412
The Prevalence of Group B streptococcus Rectovaginal Colonization and Antimicrobial Susceptibility Pattern Among Pregnant Women: A Descriptive-Analytical Study
Ghanbarzadeh N, Mehramiz M, Gannadkafi M, Namaei MH. The Prevalence of Group B streptococcus Rectovaginal Colonization and Antimicrobial Susceptibility Pattern Among Pregnant Women: A Descriptive-Analytical Study. Mod Care J. 2017;14(3):e66391. doi: https://doi.org/10.5812/modernc.66391
Isolation and Characterization of Streptococcus agalactiae and its Capsular Antigen, Along with Mycoplasma hominis and Listeria monocytogenes, as Abundant Infections in Women with Abortion in Iran
Bayat A, Doudi M, Ahadi AM, Ghasemi Tehrani H. Isolation and Characterization of Streptococcus agalactiae and its Capsular Antigen, Along with Mycoplasma hominis and Listeria monocytogenes, as Abundant Infections in Women with Abortion in Iran. Jundishapur J Microbiol. 2023;16(10):e141748. doi: https://doi.org/10.5812/jjm-141748
Direct Identification of Streptococcus agalactiae in Vaginal Colonization in Pregnant Women Using Polymerase Chain Reaction
Yousefi Mashouf R, Mousavi SM, Rabiee S, Alikhani MY, Arabestani MR. Direct Identification of Streptococcus agalactiae in Vaginal Colonization in Pregnant Women Using Polymerase Chain Reaction. J Compr Ped. 2014;5(4):e23339. doi: https://doi.org/10.17795/compreped-23339
- Scopus by DOI: 0
Last Update: 1 day ago
- Scopus by Title: 6
Last Update: 1 day ago
- Scopus by Title (Ref): 6
Last Update: 1 day ago
- CrossRef: 0
Last Update: 6 days ago
Ordering Reprints
Articles are published under the Creative Commons license stated on each article. No permission or royalty fee is required for uses permitted by that license. CCC handles optional bulk and customized reprint orders. Any quotation covers production and delivery services only, not copyright permission. > Request Reprints from CCC
Author(s):