Intraocular pressure changes due to Succinyl-Choline and Atracuriom usage before and after operation with general anesthesia

Introduction . Intraocular pressure (lOP) produced by the aqueous humor secret ion, choro idal volume changes and tonocity of extraocular muscles. This pressure is 15 mmHg. Many factors such as age, sex and anesthet ic drugs affect on lOP. Elevation of lOP dur ing the eye operation restrics the operation and sometimes causes a ser ious complicat ion of expulsive hemmorhage. In this study, the effe cts of two muscle relaxants Atracuriom and Succinyll-Choline drugs usually used in general anesthesia on lOP were compared. Materials and Methods. 70 candidates for operation at the age of 50Y/O or less were selected. They were divided in two groups. The first group received Atracurium and the second ones Succinyl-Choline. lOP was measured three times before, during and after the operation by Schiotz tonometer. Results . lOP changes in the Atracuriom group from the first to the second stage (P = 0.71), the second to the third stage (P = 0.44) and the first to the third stage (P = 0.58) were not significant. lOP change in the Succinyl-Choline group from the first to the second stage (P= 0.002) and the second to the third stage (P= 0.001) were significant, but from the first to the third stage (P= 0.77) were not. Conclusion . Succinyl-Choline, the depolarizing muscle relaxant, causes more lOP changes in comparison with Atracuriom, the non-depolarizing muscle relaxant , during the operatio n.