Effects of intermittent and continuous injections of oxytocin on labor time and maternal and neonatal outcomes in normal delivery

Author(s):
Maryam SinaMaryam Sina, Mojgan RahmanianMojgan Rahmanian,*, majid mirmohammadkhanimajid mirmohammadkhani

Koomesh:Vol. 20, issue 4; 633-637
Published online:Mar 07, 2018
Article type:Research Article
Received:Oct 03, 2017
Accepted:May 07, 2018
How to Cite:Sina M, Rahmanian M, mirmohammadkhani M. Effects of intermittent and continuous injections of oxytocin on labor time and maternal and neonatal outcomes in normal delivery. koomesh. 2018;20(4):e153004. doi:

Abstract

References

  • 1.
    Arrowsmith S, Wray S. Oxytocin: its mechanism of action and receptor signalling in the myometrium. J Neuroendocrinol 2014; 26: 356-369.
  • 2.
    Enck P, Klosterhalfen S. The story of Ois oxytocin the mediator of the placebo response? Neurogastroenterol Motil 2009; 21: 347-350.
  • 3.
    Phaneuf S, Asboth G, Carrasco M, Europe-Finner G, Saji F, Kimura T, Harris A, Bernal AL. The desensitization of oxytocin receptors in human myometrial cells is accompanied by down-regulation of oxytocin receptor messenger RNA. J Endocrinol 1997; 154: 7-18.
  • 4.
    Begum LN, Sultana M, Nahar S, Begum R, Barua S. A randomized clinical trial on the need of continuing oxytocin infusion in active phase of induced labour. Chattagram Maa-O-Shishu Hosp Med Coll J 2013; 12: 23-30.
  • 5.
    Yazdiha MS, Ghorbani R, Behshad J, Hoseini SM, Razavi M, Emadi A. Relationship between idiopathic hypercalciuria and urinary tract infection in children of 1-14 years of age. Koomesh 2016; 18: 153-158. (Persian).
  • 6.
    Noripour S, Molaei A, Bandari R, Emadi A, Far SMF, Forozeshfard M. Comparison of the results of simultaneous surfactant administration and nasal continuous positive airway pressure (INSURE) and Non-administration of surfactant for the treatment of infants with respiratory distress syndrome. J Comprehensive Pediatr 2017; 8. (Persian).
  • 7.
    Cunningham F, Leveno K, Bloom S, Spong CY, Dashe J. Williams obstetrics, 24e: Mcgraw-hill; 2014.
  • 8.
    Lee HJ, Macbeth AH, Pagani JH, Young 3rd WS. Oxytocin: the great facilitator of life. Prog Neurobiol 2009; 88: 127-151.
  • 9.
    Mercer B, Pilgrim P, Sibai B. Labor induction with continuous low-dose oxytocin infusion: a randomized trial. Obstet Gynecol 1991; 77: 659-663.
  • 10.
    Ustunyurt E, Ugur M, Ustunyurt BO, Iskender TC, Ozkan O, Mollamahmutoglu L. Prospective randomized study of oxytocin discontinuation after the active stage of labor is established. J Obstet Gynaecol Res 2007; 33: 799-803.
  • 11.
    Blakemore KJ, Qin NG, Petrie RH, Paine LL. A prospective comparison of hourly and quarterhourly oxytocin dose increase intervals for the induction of labor at term. Int J Gynecol Obstet 1990; 33: 387.
  • 12.
    Bahadoran P, Falahati J, Shahshahan Z, Kianpour M. The comparative examination of the effect of two oxytocin administration methods of labor induction on labor duration stages. Iran J Nurs Midwifery Res 2011; 16: 100-105.
  • 13.
    Girard B, Vardon D, Creveuil C, Herlicoviez M, Dreyfus M. Discontinuation of oxytocin in the active phase of labor. Acta Obstet Gynecol Scandinavica 2009; 88: 172-177.
  • 14.
    DanielSpiegel E, Weiner Z, BenShlomo I, Shalev E. For how long should oxytocin be continued during induction of labour? BJOG:2004; 111: 331-334.
  • 15.
    ztrk FH, Ylmaz SS, Yalvac S, Kandemir . Effect of oxytocin discontinuation during the active phase of labor. J Matern Fetal Neonatal Med 2015; 28: 196-198.

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