Polio-Specific Immunoglobulin G Antibodies among Children in Jos, Nigeria

Author(s):
N Dashe N Dashe *,+

Shiraz E-Medical Journal:Vol. 11, issue 4; 183-190
Published online:Oct 04, 2010
Article type:Research Article
Received:Jan 10, 2010
Accepted:Jul 24, 2010
How to Cite:Dashe N. Polio-Specific Immunoglobulin G Antibodies among Children in Jos, Nigeria. Shiraz E-Med J. 2010;11(4):20411. doi:

Abstract

Background:

Concerns on the safety of polio vaccine in some parts of northern Nigeria that led to the suspension of the immunization efforts in those parts of the country, informed our design of this prospective study.

Objective:

To determine polio-specific Immunoglobulin G antibodies among children (seven months - seven years) in Jos.

Methods:

Within the months of March and April 2007, One hundred and eighty two blood samples were collected from children in the Emergency Peadiatric Unit of the Jos University Teaching Hospital and tested for the presence of polio-specific IgG antibodies using Poliomyelitis IgG ELISA Test Kit produced and described by DEMEDITEC Diagnostic GmbH Germany

Results:

One hundred and seventy eight percent (97.8%) of the tested children had detectable antibodies against poliovirus. The study population had appreciable levels of protection against poliovirus. There was no significant association between the detection of the IgG in children in relation to gender, age, religion, and number of doses. Only educational status of fathers had statistically significant relationship with the detection of the antibodies.

Conclusion:

This study demonstrated that progress has been made towards the eradication of poliomyelitis in Nigeria. To further strengthen the gains made and weaken the barriers to immunization, there is an increasing need for more funding to increase awareness and intensify the final efforts targeted at kicking polio out of Nigeria.

Full Text

Full text is available in PDF

Similar Articles

15
Apr
2024
Arch Pediatr Infect Dis

Seroprevalence of Measles and Rubella IgG Antibodies in Children and Pregnant Women in Iran

Sedigheh Rafiei Tabatabaei,
Abdollah Karimi,
Masoud Alebouyeh,
Ghazal Zahed,
Eiman Faghihian,
Yalda Jefrideh
,et al.

Rafiei Tabatabaei S, Karimi A, Alebouyeh M, Zahed G, Faghihian E, et al. Seroprevalence of Measles and Rubella IgG Antibodies in Children and Pregnant Women in Iran. Arch Pediatr Infect Dis. 2024;12(2):e140365. doi: https://doi.org/10.5812/apid-140365

1
Jan
1970

Assessment of Maternofoetal Transfer of Antitetanus Immunoglobulin G in Jos University Teaching Hospital (JUTH), Jos

Usman Adabara Nasiru

Adabara Nasiru U. Assessment of Maternofoetal Transfer of Antitetanus Immunoglobulin G in Jos University Teaching Hospital (JUTH), Jos. Shiraz E-Med J. 1970;11(2):20365. doi:

8
Sep
2012

Seroprevalence of measles, mumps and rubella Antibodies in 18 months and 6.5 years old children: 6 months after measles-mumps-rubella (MMR) vaccination

Ahmad Shamsizadeh,
Roya Nikfar,
Manoochehr Makvandi,
Makvandi Hakimzadeh,
Mohsen Alisamir,
Tahereh Ziaei

Shamsizadeh A, Nikfar R, Makvandi M, Hakimzadeh M, Alisamir M, et al. Seroprevalence of measles, mumps and rubella Antibodies in 18 months and 6.5 years old children: 6 months after measles-mumps-rubella (MMR) vaccination. Jundishapur J Microbiol. 2012;5(4):578-581. doi: https://doi.org/10.5812/jjm.4563

13
Apr
2019
83565

Hepatitis B Seroconversion Rate After Primary Immunization Series with Newly Introduced Pentavalent Vaccine: A Report of Local Study in Alborz Province, Iran, 2016

Reza Arjmand,
Mehri Gholami,
Fariba Shirvani,
Kumars Pourrostami,
Omid Safari,
Nasrin Elahimehr
,et al.

Arjmand R, Gholami M, Shirvani F, Pourrostami K, Safari O, et al. Hepatitis B Seroconversion Rate After Primary Immunization Series with Newly Introduced Pentavalent Vaccine: A Report of Local Study in Alborz Province, Iran, 2016. Arch Pediatr Infect Dis. 2019;7(2):e83565. doi: https://doi.org/10.5812/pedinfect.83565

1
Dec
2013

Post-Vaccination Immunity Against Measles in Under Twenty-Five-Year-Old Population of Ahvaz, Southwest of Iran

Abdolhussein Shakurnia,
Seyed Mohammad Alavi,
Reza Norouzirad,
Amir Arsalan Sarajian,
Ghodratollah Shakerinejad

Shakurnia A, Alavi SM, Norouzirad R, Sarajian AA, Shakerinejad G. Post-Vaccination Immunity Against Measles in Under Twenty-Five-Year-Old Population of Ahvaz, Southwest of Iran. Jundishapur J Microbiol. 2013;6(10):e7707. doi: https://doi.org/10.5812/jjm.7707

Share on
Cited by
Metrics

Ordering Reprints

Articles are published under the Creative Commons license stated on each article. No permission or royalty fee is required for uses permitted by that license. CCC handles optional bulk and customized reprint orders. Any quotation covers production and delivery services only, not copyright permission. > Request Reprints from CCC