Survey of Complications of Triple Vaccine in Yazd in 2005

Background: Simultaneous immunization against diphtheria, tetanus and pertussis during infancy and childhood has been a routine practice in Iran. According to WHO protocol, report of adverse reactions of vaccination as side- effects to collect information and incidence of them must be done. Objective: to determine the complications of triple vaccine in referrals of the health centers of Yazd in 2005.

Methods: This cross sectional and descriptive study was carried out on all of 474 cases with DPT vaccination. The probably complications during 72h followed and observed symptoms were collected in questionnaire and the data were analyzed statically.

Results: In 474 vaccinated children, complications had been seen in 81.430% (n=386). they were 185 (80.79%) boys and 201 (82.04%) girls. the most children were who received 1st time and 1st repetitive time. most prevalent complications were fever(56.8%), pain in the injection area (55%), swelling (26.8%), crying (11.4%), loss of appetite (11.2%), non-humorous behavior (11%), erythema (10.5%), and vomiting (6.5%). the other side effects were: persistant crying, injection site erythma, vomiting an d lethargy.

Conclusion: complications after triple vaccination were rather high in Yazd. So it is recommended to recognize the causative factors and its reduction