Isolation of Enteropathogenic Escherichia coli from Children with Diarrhoea Attending the National Hospital in Abuja, Nigeria

YT Kandakai-Olukemi; JD Mawak; MM Onojo

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Abstract
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Isolation of Enteropathogenic Escherichia coli from Children with Diarrhoea Attending the National Hospital in Abuja, Nigeria

Author(s):

YT Kandakai-Olukemi^1,*,

JD Mawak¹,

MM Onojo²

1Associate Professor, Department of Medical Microbiology, Faculty of Medical Sciences,

2BSc Student, Department of Microbiology, Faculty of Natural Sciences, University of Jos, Jos, Nigeria.

Shiraz E-Medical Journal:Vol. 10, issue 3; e93762

Published online:Jul 01, 2009

Article type:Research Article

Received:May 15, 2019

Accepted:May 29, 2009

How to Cite:Kandakai-Olukemi Y, Mawak J, Onojo M. Isolation of Enteropathogenic Escherichia coli from Children with Diarrhoea Attending the National Hospital in Abuja, Nigeria. Shiraz E-Med J. 2009;10(3):e93762. doi:

Abstract

Background:: Diarrhoeal diseases remain one of the leading causes of childhood morbidity
and mortality in most developing countries, with enteropathogenic Escherichia coli (EPEC)
being one of the most important aetiologic agents of infantile diarrhoea in many of these
countries.

Objective:: To determine the prevalence of EPEC in children (0-24 months) with diarrhoea.

Methods:: One hundred stool samples from children with diarrhoea attending the National
Hospital in Abuja, Nigeria were analysed for the presence of EPEC using standard bacteriological
methods. Isolates were also subjected to antimicrobial testing using the disc diffusion
method.

Results:: Fifteen (15.00%) samples were positive for EPEC. The highest number of isolates
was recovered from the 6-12 months age group with 10 (20.41%) in total. No isolates were
recovered from the 0-5 months age group or from exclusively breast fed children, however,
nine (19.15%) children receiving mixed feeding and six (33.33%) children who were not
being breast-fed tested positive for EPEC, and the difference was found to be statistically
significant (P<0.05). The highest number of isolates, eight (53.33%), belonged to those in
the poly 1 sero-group with serotypes O1, O26, O86a, O111, O119, O127 and O128. Fourteen
(93.33%) of the isolates were sensitive to norfloxacin, 13 (86.67%) each to ofloxacin and
colistin, 11 (73.33%) to nalidixic acid, 10 (66.67%) to cefuroxime, two (13.33%) to cotrimoxazole,
and one (6.67%) to tetracycline. None of the isolates were found to be sensitive to
ampicillin or chloramphenicol.

Conclusion:: This study has shown that multidrug resistant EPEC is associated with infantile
diarrhoea in Abuja, Nigeria. To address this issue, antibiotic therapy should take into consideration
the susceptibility pattern of the pathogen. In addition, the incidence of EPEC in children
can be traced primarily to faulty weaning practices and/or poor personal hygiene.

Keywords

Enteropathogenic Escherichia coli (EPEC)

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References

1.
The references are available in the PDF file.

Frequency, antimicrobial susceptibility and plasmid profiles of Escherichia coli pathotypes obtained from children with acute diarrhea

Enayat Kalantar,

Fariborz Soheili,

Heiman Salimi,

Mohammad Mehdi Soltan Dallal

Kalantar E, Soheili F, Salimi H, Soltan Dallal MM. Frequency, antimicrobial susceptibility and plasmid profiles of Escherichia coli pathotypes obtained from children with acute diarrhea. Jundishapur J Microbiol. 2011;4(1):. doi:

2

Dec

2017

Characterization of Toxins and Colonization Factors of Enterotoxigenic Escherichia coli Isolates from Children with Acute Diarrhea in Abuja, Nigeria

Casmir Ifeanyichukwu Cajetan Ifeanyi,

Nkiruka Florence Ikeneche,

Bassey Enya Bassey,

Nazek Al-Gallas,

Akpa Alexander Casmir,

Isu Rosemary Nnennaya

Ifeanyichukwu Cajetan Ifeanyi C, Ikeneche NF, Bassey BE, Al-Gallas N, Alexander Casmir A, et al. Characterization of Toxins and Colonization Factors of Enterotoxigenic Escherichia coli Isolates from Children with Acute Diarrhea in Abuja, Nigeria. Jundishapur J Microbiol. 2018;11(1):e64269. doi: https://doi.org/10.5812/jjm.64269

17

Dec

2024

The Prevalence of Typical and Atypical Enteropathogenic Escherichia coli Strains Isolated from Non-diarrheal Stool Samples of Children of Tehran

Saba Farhadinia,

Shahin Najarpiraye,

Bita Bakhshi

Farhadinia S, Najarpiraye S, Bakhshi B. The Prevalence of Typical and Atypical Enteropathogenic Escherichia coli Strains Isolated from Non-diarrheal Stool Samples of Children of Tehran. Jundishapur J Microbiol. 2024;17(12):e151793. doi: https://doi.org/10.5812/jjm-151793

12

Mar

2018

Antimicrobial Susceptibility Patterns of Enteroaggregative <i>E. coli</i>, as the Most Common Diarrheagenic <i>E. coli</i>, Associated to Gastroenteritis Outbreaks in Iran

Antimicrobial Susceptibility Patterns of Enteroaggregative E. coli, as the Most Common Diarrheagenic E. coli, Associated to Gastroenteritis Outbreaks in Iran

Mohammad Mehdi Soltan-Dallal,

Mohsen Karami-Talab,

Maneli Aminshahidi,

Amir Arastehfar,

Fereshteh Fani

Soltan-Dallal MM, Karami-Talab M, Aminshahidi M, Arastehfar A, Fani F. Antimicrobial Susceptibility Patterns of Enteroaggregative E. coli, as the Most Common Diarrheagenic E. coli, Associated to Gastroenteritis Outbreaks in Iran. Arch Pediatr Infect Dis. 2018;6(2):e11917. doi: https://doi.org/10.5812/pedinfect.11917

30

Jun

2000

Prevalence of diarrhea caused by Enteropathogenic E.Coli in under one year old children

M Nasrolahi,

M Sharif

Nasrolahi M, Sharif M. Prevalence of diarrhea caused by Enteropathogenic E.Coli in under one year old children. J Inflamm Dis. 2024;4(1):e154699. doi:

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YT Kandakai-Olukemi:[PubMed][Scholar]
JD Mawak:[PubMed][Scholar]
MM Onojo:[PubMed][Scholar]

Outlines

Isolation of Enteropathogenic Escherichia coli from Children with Diarrhoea Attending the National Hospital in Abuja, Nigeria

Abstract

Fulltext

References

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