Laboratory Diagnosis of Myeloperoxidase Deficiency: A Case Report.

Author(s):
Zahra PourmehdiZahra Pourmehdi1, Seyedkamaleddin TabatabaeiSeyedkamaleddin Tabatabaei2, Seyedahmadreza SalimbahramiSeyedahmadreza Salimbahrami1,*, Shiva BorzoueiShiva Borzouei3
1Professor, Hematology and Oncology Resarch Center, Tabriz University of Medical Sciences
2Clinica Fellow, Hematology and Oncology Resarch Center, Tabriz University of Medical Sciences
3Research Assistant, Hematology and Oncology Resarch Center, Tabriz University of Medical Sciences
*Corresponding Author: Hematology and Oncology Research Center, Daneshgah Street, Imam Reza Educational and Treatment Center, Shahid Ghazi Hospital, Tabriz, Iran, Tel.: +98(411)3343-811, Fax: +98(411)334-3844, E-mail: [email protected]. Email: [email protected]

Shiraz E-Medical Journal:Vol. 13, issue 1; e93925
Published online:Jan 01, 2012
Article type:Case Report
Received:May 18, 2019
Accepted:Dec 10, 2011
How to Cite:Pourmehdi Z, Tabatabaei S, Salimbahrami S, Borzouei S. Laboratory Diagnosis of Myeloperoxidase Deficiency: A Case Report.. Shiraz E-Med J. 2012;13(1):e93925. doi:

Abstract

Myeloperoxidase deficiency is a common disorder featuring deficiency, either in quantity or function of Myeloperoxidase. The patients are misdiagnosed because majority of individuals with Myeloperoxidase deficiency show no signs of immunodeficiency. Myeloperoxidase defi-ciency is noted even before the diagnosis is suspected because the machines that perform automated leukocyte differential counts rely upon neutrophil Myeloperoxidase activity to enumerate these cells. This report describes two cases of myeloperoxidase deficiency that were diagnosed after reassess of the hemograms.In one case ,we got to the diagnosis after the patient went under Bone marrow Aspiration for ruling out leukemia.

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Copyright

© 2012, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.

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