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Zahedan Journal of Research in Medical Sciences
The Official Journal of Zahedan University of Medical Sciences
e-ISSN 2383-2894
Image Credit:Zahedan J Res Med Sci
Outline
Serum Level of Trace Elements (Zinc, Lead, and Copper), Albumin and Immunoglobulins in Asthmatic Children
Authors
1Department of Pediatrics, Mazandaran University of Medical Sciences, Sari, Iran
2Inflammation and Inflammatory Diseases Research center, Mashhad University of Medical Sciences, Mashhad, Iran
3Department of Obstetrics and Gynecology, Mazandaran University of Medical Sciences, Sari, Iran
*Corresponding Author: Department of Pediatrics, Mazandaran University of Medical Sciences, Sari, Iran Email: javadneg@yahoo.com
Published online:May 20, 2013
Article type:Research Article
Received:Feb 09, 2013
Accepted:Apr 18, 2013
How to Cite:Ghaffari J, Rafatpanah H, Nazari Z, Abaskhanian A. Serum Level of Trace Elements (Zinc, Lead, and Copper), Albumin and Immunoglobulins in Asthmatic Children. Zahedan J Res Med Sci. 2013;15(9):e92851. doi:
Abstract
Background : Bronchial asthma (BA) is a chronic inflammatory disease and it is a major health problem. Trace elements such as copper and zinc are essential components of anti-oxidant enzymes and optimal function of the immune response. Changes in the levels of these elements may lead to increase the risk of asthma.
Materials and Methods : The study group consisted of 175 asthmatic children and 165 control group of healthy general population who attend the outpatient allergic clinic (Bou Ali Hospital) in Sari, Mazandaran, Iran between August 2010 and March 2011. Complete blood count, eosinophil count and serum total IgE level and Serum trace element levels (Zinc, lead and copper) were measured in both groups.
Results : There was a significant difference in serum levels of copper, lead, IgE (increased), and decreased IgA, between two groups (p=0.001). There was no significant difference in blood zinc levels and eosinophilia between two groups (p=0.732 and 0.068, respectively).
Conclusion : Increased serum levels of copper and lead may be associated with asthma.
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Copyright
© 2013, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.
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