Fulltext
The full text of this article is available on the PDF file.
Zahedan Journal of Research in Medical Sciences
The Official Journal of Zahedan University of Medical Sciences
e-ISSN 2383-2894
Image Credit:Zahedan J Res Med Sci
Outline
Evaluation of Antifungal Activity of Methanol Extract of Acacia (Anagalis Arvensis) Leaves and Nystatin against Candida Albicans in Vitro
Authors
Mohammad Reza Majid Khoshkholgh-Pahlaviani1,*, Ali Reza Massiha2, Khosro Issazadeh3, Siroos Bidarigh4, Masoud Giahi5, Maryam Ramtin6
1Department of Clinical Bacteriology, Faculty of Basic Sciences, Islamic Azad University of Lahijan Branch, Lahijan, Iran
2Department of Biotechnology, Faculty of Basic Sciences, Islamic Azad University of Lahijan Branch, Lahijan, Iran
3Department of Microbiology, Faculty of Basic Sciences, Islamic Azad University of Lahijan Branch, Lahijan, Iran
4Department of Agriculture, Faculty of Natural Resource, Islamic Azad University of Lahijan Branch, Lahijan, Iran
5Department of Chemistry, Faculty of Basic Sciences, Islamic Azad University of Lahijan Branch, Lahijan, Iran
6Department of Microbiology, Member of Young Researchers Club, Islamic Azad University of Lahijan, Lahijan, Iran
*Corresponding Author: Department of Clinical Bacteriology, Faculty of Basic Sciences, Islamic Azad University of Lahijan Branch, Lahijan, Iran Email: lionface2006@yahoo.com
Published online:Dec 30, 2012
Article type:Research Article
Received:Apr 20, 2011
Accepted:Sep 07, 2011
How to Cite:Majid Khoshkholgh-Pahlaviani MR, Massiha AR, Issazadeh K, Bidarigh S, Giahi M, et al. Evaluation of Antifungal Activity of Methanol Extract of Acacia (Anagalis Arvensis) Leaves and Nystatin against Candida Albicans in Vitro. Zahedan J Res Med Sci. 2013;15(8):e92906. doi:
Abstract
Background: Anagalis is the name of Scarlet Pimpernel, with about 20 to 25 species of flowering plants in the family Myrsinaceae. The common variety (A. arvensis) is a low-growing annual plant found in Europe, Asia and North America. In this Investigation, the inhibitory effects of methanol extract of Anagalis arvensis leaves and drug nystatin on clinical isolates and standard strain of Candida albicans (14053 PTCC) isolated from patients with vulvovaginal candidiasis were studied.
Materials and Methods: In the laboratory study of 45 clinical isolates of Candida albicans was used and inhibitory effects of the extract were evaluated using by serial dilution Method. Chemical compounds of A. arvensis extract including alkaloids, glycosides, phenolic compounds, Terpenoids and amino acids were identified
Results: The results showed that the minimum inhibitory concentration (MIC) nystatin against clinical isolates and standard strain of Candida albicans were similar and drug nystatin revealed the better MIC against standard strain and clinical isolates of C. albicans. Methanol extract of A. arvensis were inhibitory on standard strain and clinical isolates of C. albicans. The minimum inhibitory concentration of extract in comparison with the drug nystatin was less while the composition of the growth inhibitory concentration was greater than drug solely
.
Conclusion: This study indicated that the antimicrobial activity of this plant extract was considerable compared to drug nystatin and it demonstrate a basis for further research to isolate the active components in a variety of microbial strains
.
.
Highlights
References
- 1.The References of this article are available on the PDF file.
Copyright
© 2013, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.
Similar Articles
31
Dec
2016
Comparing antifungal effects of Zatariamultiflora and Punicagranatum extract with Nystatin on Candida Albicans
F Nouri,
Arash mansourian
Nouri F, mansourian A. Comparing antifungal effects of Zatariamultiflora and Punicagranatum extract with Nystatin on Candida Albicans. J Inflamm Dis. 2024;20(5):e155988. doi:
20
Feb
2016
Antifungal Effect of the Aqueous and Ethanolic Avicennia marina Extracts on Alternaria citri and Penicillium digitatum
Behrooz Alizadeh Behbahani,
Farideh Tabatabaei Yazdi,
Fakhri Shahidi,
Fatemeh Riazi
Alizadeh Behbahani B, Tabatabaei Yazdi F, Shahidi F, Riazi F. Antifungal Effect of the Aqueous and Ethanolic Avicennia marina Extracts on Alternaria citri and Penicillium digitatum. Zahedan J Res Med Sci. 2016;18(2):e5992. doi: https://doi.org/10.17795/zjrms-5992
13
Jul
2021
Evaluation of Antimicrobial Activity of Some Medicinal Plants on Human Standard Bacteria and Candida albicans
Bahman Fazeli-Nasab,
Ahmad Farid Rahmani,
Moharram Valizadeh,
Hamideh Khajeh,
Maryam Beigomi
Fazeli-Nasab B, Rahmani AF, Valizadeh M, Khajeh H, Beigomi M. Evaluation of Antimicrobial Activity of Some Medicinal Plants on Human Standard Bacteria and Candida albicans. Gene Cell Tissue. 2021;8(3):e113092. doi: https://doi.org/10.5812/gct.113092
31
May
2017
Antifungal activity of essential oils of Prangos frulacea, Ziziphora tenuior, Ferula gummosa and Dracocephalum moldavica against candida albicans
bahareh nazemisalman,
alireza yazdinezhad,
S Salah,
N Sajedinejad
nazemisalman B, yazdinezhad A, Salah S, Sajedinejad N. Antifungal activity of essential oils of Prangos frulacea, Ziziphora tenuior, Ferula gummosa and Dracocephalum moldavica against candida albicans. J Inflamm Dis. 2024;21(1):e156005. doi:
18
Aug
2015
In Vitro Antifungal Activity of Various Persian Cultivars of Punica granatum L. Extracts Against Candida species
Shahindokht Bassiri-Jahromi,
Farzad Katiraee,
Mannan Hajimahmoodi,
Ehsan Mostafavi,
Malihe Talebi.,
Mohammad Reza Pourshafie
Bassiri-Jahromi S, Katiraee F, Hajimahmoodi M, Mostafavi E, Talebi. M, et al. In Vitro Antifungal Activity of Various Persian Cultivars of Punica granatum L. Extracts Against Candida species. Jundishapur J Nat Pharm Prod. 2015;10(3):e19754. doi: https://doi.org/10.17795/jjnpp-19754
Cited by
- Scopus by DOI: 0
Last Update: 1 week ago
- Scopus by Title: 0
Last Update: 1 week ago
- Scopus by Title (Ref): 0
Last Update: 1 week ago
- CrossRef: 0
Last Update: 6 hours ago
- OpenAlex: 0
Last Update: 10 hours ago
- OpenCitations: 0
Last Update: 5 days ago
Comments
Number of Comments:0