Prevalence of Helicobacter Pylori Infection in Children, a Population-Based Cross-Sectional Study in West Iran

Jafar  Soltani; Jalil Amirzadeh; Soheila Nahedi; Sirous Shahsavari

IJ Pediatrics

The Scientific Journal of Growth & Development Research Center

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Prevalence of Helicobacter Pylori Infection in Children, a Population-Based Cross-Sectional Study in West Iran

Author(s):

Jafar Soltani^1,*,

Jalil Amirzadeh²,

Soheila Nahedi³,

Sirous Shahsavari⁴

IJ Pediatrics:Vol. 23, issue 1; 13-18

Published online:Dec 12, 2012

Article type:Research Article

Received:Feb 23, 2012

Accepted:Jun 23, 2012

How to Cite:Jafar SoltaniJalil AmirzadehSoheila NahediSirous ShahsavariPrevalence of Helicobacter Pylori Infection in Children, a Population-Based Cross-Sectional Study in West Iran.Iran J Pediatr.23(1):13-18.

Abstract

Objective: In developing countries, Helicobacter pylori infection is mainly acquired during childhood and may be a predisposing factor for peptic ulcer or gastric cancer later in life. Non¬invasive diagnostic tools are particularly useful in children for screening tests and epidemiological studies. We aimed to determine the prevalence of H. pylori infection among Kurdish children in Sanandaj, West Iran.
Methods: We used a Helicobacter Pylori Stool Antigen (HpSA) test to detect H. pylori infection. A questionnaire was used to collect data about age, sex, duration of breastfeeding, and family size. A total of 458 children aged 4 months to 15 years were enrolled in this study.
Findings: The mean age of enrolled children was 5.6±5.4 years. Stool samples were positive for H. pylori in 294 (64.2%) children. The prevalence of H. pylori infection increased with age (P<0.001). We found a significant increase in the infection rate as the family size grew (P=0.005). There was no correlation between a positive H. pylori status and gender (P=0.6) or the duration of breastfeeding (P=0.8).
Conclusion: It seems that the prevalence of H. pylori infection is very high in children in Sanandaj. It begins at early infancy (before 4th month of age) and cumulatively increases with age.

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