Antimicrobial Activity and Composition of the Essential Oil of Cymbopogon Olivieri (Boiss.) Bor from Iran

authors:

avatar Ali Sonboli 1 , * , avatar Mohammad Hossein Mirjalili 2 , avatar Morteza Yousefzadi 3

Department of Biology, Medicinal Plants and Drugs Research Institute, Shahid Beheshti University, Tehran, Iran
Department of Agriculture, Medicinal Plants and Drugs Research Institute, Shahid Beheshti University, Tehran, Iran
Department of Ecology & Systematic, Research Institute of Applied Sciences, Tehran, Iran
Iranian Journal of Pharmaceutical Research: Vol.5, issue 1; 65-68
published online: November 20, 2010
article type: Research Article
received: January 21, 2005
accepted: February 21, 2006
DOI: https://doi.org/10.22037/ijpr.2010.655

how to cite: Sonboli A, Mirjalili M H, Yousefzadi M. Antimicrobial Activity and Composition of the Essential Oil of Cymbopogon Olivieri (Boiss.) Bor from Iran. Iran J Pharm Res. 2006;5(1):e128265. https://doi.org/10.22037/ijpr.2010.655.

Abstract

The in vitro antimicrobial activity of the essential oil isolated from the aerial parts of Cymbopogon Olivieri (Boiss.) Bor, an aromatic grass of Iran was tested against three Gram-negative and four Gram-positive bacteria and also three fungi. The results of the bioassays showed that the oil has a remarkable antimicrobial activity. Bacillus subtilis and Candida albicans were more sensitive to the oil than other microorganisms with inhibition zones of 20 mm and MIC values of 3.75 mg/ml and 2.5 mg/ml, respectively. The Gram-negative bacteria, Pseudomonas aeruginosa was resistant and Klebsiella pneumoniae showed less sensitivity to the oil with MIC value of >15 mg/ml. GC-MS analysis of the oil confirmed the determination of 40 compounds representing 95.0% of the oil. The main identified constituent was piperitone (48.9%).