Prognostic Value of Troponin T after Elective Percutaneous Coronary Intervention

A  Ghaemian; safoora Masoumi; RA  Mohammadpour

International Cardiovascular Research Journal

The Official Annually Journal of Cardiovascular Research Center, Shiraz University of Medical Sciences

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Prognostic Value of Troponin T after Elective Percutaneous Coronary Intervention

Author(s):

A Ghaemian¹,

safoora Masoumi^1,*,

RA Mohammadpour²

1Mazandaran Heart Cente, Sari, Iran

2Department of Biostatistics, Mazandaran University of Medical Sciences, Sari, Iran

International Cardiovascular Research Journal:Vol. 5, issue 1; e14234

Published online:Jun 30, 2011

Article type:Research Article

Received:May 31, 2017

Accepted:Jan 13, 2011

How to Cite:A Ghaemiansafoora MasoumiRA MohammadpourPrognostic Value of Troponin T after Elective Percutaneous Coronary Intervention.Int Cardiovasc Res J.5(1):e14234.

Abstract

Background: Cardiac troponin T (cTnT) is a sensitive and specific marker of myocardial necrosis. Prognostic significance of isolated minor elevations of cTnT is a matter of debate .The aim of this study was to assess the impact of minor elevations of cTnT on major adverse cardiac events (MACE) following percutaneous coronary intervention (PCI).

Methods: We measured cTnT levels before and after PCI and evaluated the outcomes of 112 patients with normal baseline cTnT and complex coronary artery disease who required nonemergency PCI.

Results: Elevations (more than 0.03ng/ml) in cTnT were seen in 39 patients (34.8%).The angiographic characteristics of patients with increased cTnT levels had borderline differences compared to those with normal post PCI cTnT levels. Over a mean follow-up duration of 22 months, myocardial infarction (p<0.01) and the combined rate of death, myocardial infarction and revascularization (p<0.001) were significantly higher in patients with increased levels of post PCI cTnT. Estimated 22-month MACE-free survival for patients with increased and normal cTnT levels were 66.7% and 93.2%, respectively.

Conclusion: Isolated minor elevations in cTnT after elective PCI in complex coronary lesions affect long-term prognosis regarding death, myocardial infarction and the need for repeated revascularization procedures.

Keywords

Troponin T

Percutaneous Coronary Intervention

Prognosis

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