The Outcome of Six-month Clinical Trial with Eucatax Paclitaxel Eluting Stent Compared With Eucastsflex Bare Metal Stent in Patients Undergoing De Novo Coronary Stenting

Mohammad Ali Ostovan; M  Rezaie; Javad  Kojuri

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The Outcome of Six-month Clinical Trial with Eucatax Paclitaxel Eluting Stent Compared With Eucastsflex Bare Metal Stent in Patients Undergoing De Novo Coronary Stenting

Author(s):

Mohammad Ali Ostovan¹,

M Rezaie^1,*,

Javad Kojuri¹

1Cardiovascular Research Center, Shiraz University of Medical Sciences, Shiraz, Iran

International Cardiovascular Research Journal:Vol. 4, issue 2; e65013

Published online:Jun 30, 2010

Article type:Research Article

Received:Dec 17, 2017

Accepted:Jun 30, 2010

How to Cite:Mohammad Ali Ostovan, M Rezaie, Javad Kojuri, The Outcome of Six-month Clinical Trial with Eucatax Paclitaxel Eluting Stent Compared With Eucastsflex Bare Metal Stent in Patients Undergoing De Novo Coronary Stenting.Int Cardiovasc Res J.2010;4(2):e65013.

Abstract

Background: Superiority of paclitaxel-eluting stents over bare metal stents in angiographic and clinical outcomes
have been shown in many trials . Eucatax stents is a newly developed paclitaxel eluting stent using biodegradable
polymer matrix. To our knowledge there have been no studies directly comparing Eucatax paclitaxel
eluting stents with EucaSTSflex bare metal stents. The aim of this study is to evaluate short-term benefits of
Eucatax in comparison with EucaSTSflex in patients undergoing denovo coronary stenting.
Methods: A retrospective comparison of Eucatax versus EucaSTSflex was conducted among 89 consecutive
patients (44 Eucatax, 45 EucaSTSflex) in Kowsar heart institute, with at least one successfully deployed stent in
de novo lesions over a 6-month period. Outcomes included death ,nonfatal MI, CABG, late stent thrombosis
at six month, as well as functional evidence of ischemia evaluated by exercise treadmill test(ETT) or cardiac
scan( SPECT).
Results: From April to July 2008, a total of 89 patients (44 Eucatax, 45 EucaSTSflex) were evaluated after PCI
for de novo coronary lesions.
After six month follow up no difference was observed in term of death ,MI,CABG and late stent thrombosis
between Eucatax compared with EucaSTSflex. Also a non-statistically significant lower rate of positive ETT (or
SPECT) was found in Eucatax group after six month.
Conclusion: Paclitaxel eluting stents(Eucatax)are not superior to bare metal stents(EucaSTSflex) in regard to
short-term clinical outcome.

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