Distribution of Hepatitis C Virus Genotypes Among Chronic Infected Injecting Drug Users in Tehran, Iran

Authors

Fahimeh Ranjbar KermaniFahimeh Ranjbar Kermani ORCID1, Zohreh SharifiZohreh Sharifi ORCID1,*, Fereshteh FerdowsianFereshteh Ferdowsian ORCID1, Zahrah PazZahrah Paz ORCID1, Mahsa ZamanianMahsa Zamanian ORCID1
1Blood Transfusion Research Center, High Institute for Research and Education in Transfusion Medicine, Tehran, IR Iran, [email protected]
*Corresponding Author: Blood Transfusion Research Center, High Institute for Research and Education in Transfusion Medicine, Tehran, IR Iran. Tel: +98-2188601501-30, Fax: +98-2188601555, E-mail: [email protected], [email protected]. Email: [email protected]

Jundishapur Journal of Microbiology:Vol. 6, issue 3; 265-8
Published online:Apr 30, 2013
Article type:Research Article
Received:Apr 16, 2012
Accepted:Jul 02, 2012
How to Cite:Ranjbar Kermani F, Sharifi Z, Ferdowsian F, Paz Z, Zamanian M. Distribution of Hepatitis C Virus Genotypes Among Chronic Infected Injecting Drug Users in Tehran, Iran. Jundishapur J Microbiol. 2013;6(3):. doi: https://doi.org/10.5812/jjm.5191

Abstract

Background:

Hepatitis C virus (HCV) is the main cause of infection that has the potential to cause chronic liver disease. Injecting drug users (IDUs) have a key role in HCV transmission in Iran. Knowledge of the distribution of various genotypes is essential for successful future research and control strategies.

Objectives:

The aim of this study was to identify HCV genotypes among chronic infected injecting drug users (IDUs) in Tehran, Iran.

Patients and Methods:

In this cross sectional study, we investigated HCV genotypes among 36 plasma samples from HCV infected IDUs (35 male and 1female, mean age: 33.67, and age range 20-62 years), referred to Research Center of Iranian Blood Transfusion Organization(IBTO) in Tehran from December 2008 to March 2009.HCV Genotyping was performed using type-specific primers.

Results:

Genotypes 3a, 1a and 1b were found in 58.3 %, 25% and 16.7 % patients, respectively.

Conclusions:

Our study demonstrated the high prevalence of genotype 3a among injecting drug users, which is also found in Europe and United states.

Full Text

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Copyright

© 2013, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.

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