Relative Frequency of Enteroviruses in Children With Aseptic Meningitis Referred to Aboozar Hospital in Ahvaz

11) Department of Medical Microbiology , School of Medicine , Ahvaz Jundishapur University of Medical Science, 2)Infectious and Tropical Disease Research Center, Ahvaz Jundishapur University of Medical Science, alirezasamarbaf_78@hotmail.com, IR Iran

*Corresponding Author: Abstract Full Text Copyright https://doi.org/10.5812/jjm.2359 Relative Frequency of Enteroviruses in Children With Aseptic Meningitis Referred to Aboozar Hospital in Ahvaz authors: avatar Mojtaba Rasti 1 , avatar Ali Reza Samarbaf-Zadeh 2 , * , avatar Manoochehr Makvandi 1 , avatar Ahmad Shamsi-Zadeh 1 1 Department of Medical Microbiology , School of Medicine , Ahvaz Jundishapur University of Medical Science, IR Iran 2 1) Department of Medical Microbiology , School of Medicine , Ahvaz Jundishapur University of Medical Science, 2)Infectious and Tropical Disease Research Center, Ahvaz Jundishapur University of Medical Science, alirezasamarbaf_78@hotmail.com, IR Iran * 1) Department of Medical Microbiology , School of Medicine , Ahvaz Jundishapur University of Medical Science, 2)Infectious and Tropical Disease Research Center, Ahvaz Jundishapur University of Medical Science, alirezasamarbaf_78@hotmail.com, IR Iran. Tel: +98-6113354389. Fax: +98-6113361544. Email:alirezasamarbaf_78@hotmail.com

Jundishapur Journal of Microbiology:Vol. 5, issue 3; 456-459

Published online:Jul 31, 2012

Article type:Research Article

Received:Sep 20, 2011

Accepted:Jan 10, 2012

How to Cite:Rasti M, Makvandi M, Shamsi-Zadeh A, Samarbafzadeh A. Relative Frequency of Enteroviruses in Children With Aseptic Meningitis Referred to Aboozar Hospital in Ahvaz.Jundishapur J Microbiol.2012;5(3):456-459.https://doi.org/10.5812/jjm.2359.

Abstract

Background: Human Enteroviruses are members of the Picornaviridae family, they are nonenveloped,with icosahedral symmetry, positive RNA viruses and causes aseptic meningitis in both infants and adults.
Objectives: The aim of this study was to determine the relative frequency of Enteroviral meningitis among children referred to Ahvaz Aboozar hospital.
Patients and Methods: 57 Cerebrospinal fluid samples were collected from patients with aseptic meningitis and White Blood Cell (WBC) count of more than 5x106/mm3, Enterovirus RNA was extracted with Roch extraction kit and Enteroviral infection was detected by Revers Transcriptase polymerase chain reaction (RT-PCR) test.
Results: Enteroviral infection was detected in 34 cases out of 57 patient (59.6 %), 19 patients were younger than 1 year old (55.8 %), 8 cases were between 1 and 2 years (23.5 %) and 7 cases were older than 2 years (20.5 %). The relationship between gender and prevalence was not significant. Most cases were found in winter .
Conclusions: It was shown that human Enterovirus is the major cause of aseptic meningitis in Ahvaz, south west of Iran. The prevalence of Enterovirus infection was considerably high in this region. To decrease prevalence of Enteroviral infection, improved knowledge and personal hygiene is advised.

Implication for health policy/practice/research/medical education:
The data collected in this project assist paediatricians to manage infant gastroenteritis cases more effectively.

Please cite this paper as:
Rasti M, Samarbaf-Zadeh AR, Makvandi M, Shamsi-Zadeh A. Relative Frequency of Enteroviruses in Children With Aseptic Meningitis Referred to Aboozar Hospital in Ahvaz. Jundishapur J Mirobiol. 2012;5(3):456-9. DOI: 10.5812/jjm.2359

Keywords

Human Enterovirus

Aseptic Meningitis

Reverse Transcreaptase Polymerase

Chain Reaction

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Author(s):

Mojtaba Rasti:[PubMed][Scholar]
Manoochehr Makvandi:[PubMed][Scholar]
Ahmad Shamsi-Zadeh:[PubMed][Scholar]
Alireza Samarbafzadeh:[PubMed][Scholar]