The community of social media influencers expands and possesses considerable potential and influential power over their audience (
19). Influencers can be described as thought leaders in the media (
20). Due to their credibility and distinct position, influencers or influential individuals serve as supporters and trusted figures in social media, acting as progressive agents (
21). Influencers in social networks, channels, platforms, and applications, utilizing the power of media, play a significant role in human societies. Utilizing these individuals can contribute to conveying health-centered messages (
22). The success of worldwide health programs relies on aligning goals, implementing strategies, and using tools correctly and innovatively. Coordination and alignment of strategies with culture, social norms, public awareness levels, financial resources, and the levels of engagement with actors and stakeholders are vital for any initiative. The emergence of influencer phenomena and influencer marketing has created attractive opportunities for accessing and engaging with audiences (
23). Influencer marketing is a form of native advertising that can promote various communication techniques to create promotional messages (
24). Identifying influencers on social media can significantly affect target audiences (
21). The interest of advertisers in influencer marketing is steadily growing, giving rise to increased budgeting and expenses for investing in influencers (
25). Influencers can stimulate, inspire, and motivate audiences by engaging them with posts, comments, likes, hashtags, etc. (
26). Influencer marketing is a strategic marketing process that involves researching, identifying, engaging, and supporting individuals who can generate influential conversations and interactions with audiences about a brand or behavior on social media (
27). Collaborating with these influencers provides new opportunities for interacting with audiences and offers useful applications for modeling health behaviors, promoting proper behavioral norms, and eliminating risky behaviors or breaking taboos (
23). Most healthcare brands can effectively engage their audience by providing education, findings, news, and new preventive and therapeutic techniques in an attractive and informative manner. It should be noted that establishing and facilitating cultural aspects appears to be a significant challenge in this field (
28). Since the internet inhibits many influencers, celebrities, bloggers, athletes, musicians, etc., it is quintessential to reduce this clutter and categorize and identify suitable influencers at the right time (
29). In the realm of interdisciplinary studies and the integration of sciences, there has been no effort to identify influencers in specific medical areas or explore the characteristics of influencers globally and in Iran, particularly in healthcare and medical services. Since countries have diverse cultures and population segments, it is crucial to properly examine geographical regions, residents' awareness levels, cultures, religions, and traditions to develop successful strategies through influencers and regional and global programs and strategies. Influencers can play a pivotal role in the success or failure of such programs (
30). The presence of influencers in international programs, including those designed by the World Health Organization, can significantly contribute to cost reduction.