Cover image of the article: Proptosis and Facial Palsy as an Unusual Clinical Presentation of Acute Myeloid Leukemia

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Proptosis and Facial Palsy as an Unusual Clinical Presentation of Acute Myeloid Leukemia

Authors

D S Takhenchangbam1, Rajesh Singh Laishram2,*, T S Thoudem1, A Sunita1, L T Imchen1
1Dept. of Radiotherapy, Regional Institute of Medical Sciences, Imphal, Manipur, India
2Dept. of Pathology, Regional Institute of Medical Sciences, Imphal, Manipur, India
*Corresponding Author: Corresponding author: Rajesh Singh Laishram, Dept. of Pathology, Regional Institute of Medical Sciences, Imphal, Manipur, India, Tel: +91-9436039201, E-mail: Email: rajeshlaishr@gmail.com

International Journal of Cancer Management:Vol. 6, issue 1; e80388
Published online:Mar 30, 2013
Article type:Case Report
Received:Mar 09, 2012
Accepted:Jul 20, 2012
How to Cite:Takhenchangbam DS, Laishram RS, Thoudem TS, Sunita A, Imchen LT. Proptosis and Facial Palsy as an Unusual Clinical Presentation of Acute Myeloid Leukemia. Int J Cancer Manag. 2013;6(1):e80388. doi:

Abstract

Simultaneous proptosis and facial palsy as the clinical presentation of childhood Acute Myeloid Leukaemia (AML) is very rare. To date, no case have been reported anywhere to the best of our knowledge. Extra medullary leukemic deposits or Granulocytic Sarcoma (GS) is a rare manifestation in about 3% of childhood AML, 9.3% of GS manifested as orbit deposits causing proptosis in one or both eyes. CNS infiltration or acute otomastoiditis subsequent to leukemic infiltration of the temporal bone may be implicated with facial paralysis. We are here with reporting the case in a 3-year-old boy who presented with proptosis and facial palsy in a case of AML. The purpose of reporting this case is to emphasize the need of examining the peripheral blood and bone marrow in children presenting as proptosis and facial palsy for early diagnosis of childhood AML.

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© 2013, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.

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