Left Ventricular Hypertrophy in Fabry's Disease in an Old Male Patient

Author(s):
Abdul  Razak Abdul Razak 1,*, Maryam Said Mohamed Al HajriMaryam Said Mohamed Al Hajri1, K Ranjan ShettyK Ranjan Shetty1, Krishnananda NayakKrishnananda Nayak1
1Department of Cardiology Kasturba medical college Manipal, India
*Corresponding Author: *Corresponding author: Department of Cardiology, Kasturba Medical College, Manipal, India. Tel.: +91-9448252641, E-mail: Email: [email protected]

International Journal of Cardiovascular Practice:Vol. 3, issue 3; 50-56
Published online:Oct 12, 2018
Article type:Case Report
Received:Aug 19, 2018
Accepted:Aug 31, 2018
How to Cite:Razak A, Said Mohamed Al Hajri M, Shetty KR, Nayak K. Left Ventricular Hypertrophy in Fabry's Disease in an Old Male Patient. Int J Cardiovasc Pract. 2018;3(3):e130283. doi: https://doi.org/10.21859/ijcp-03033

Abstract

introduction: Atrial septal defects (ASD) considered being one of the known congenital heart diseases. ASD causes increased volume overload of the right heart. The purpose of this study was to evaluate left ventricular (LV) torsion deformation in ASD patients undergoing transcatheter device closure.

Methods: All adult patients who underwent transcatheter device closure with ostium secundum ASD were included in the study. We assessed LV torsion in ostium secundum ASD patient’s pre and post device closure by using speckle tracking echocardiography.

Results: A total of 37 patients (22 females and 15 males) were included in this study. The average age was 28 ± 19 years. LV peak basal rotation improved significantly (P = 0.028) in post transcatheter closure. LV torsion (2.88 ± 0.99˚/cm before vs. 3.40 ± 1.41˚/cm after closure, P = 0.009) and twisting (15.12 ± 4.69˚ before vs. 17.95 ± 6.21˚ after closure, P = 0.005) were statistically significant in post transcatheter closure. Volumetric assessment of LV including end-diastolic volume and systolic volume showed significant improvement (P = 0.02, P < 0.01) post device closure.

Conclusions: The increased peak LV twisting and torsion was mainly attributed to the improved peak systolic clockwise rotation after ASD device closure. The LV twisting at a younger age was improved after the closure of ASD

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© 2018, International Journal of Cardiovascular Practice. This open-access article is available under the Creative Commons Attribution-NonCommercial 4.0 (CC BY-NC 4.0) International License (https://creativecommons.org/licenses/by-nc/4.0/), which allows for the copying and redistribution of the material only for noncommercial purposes, provided that the original work is properly cited.

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