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International Journal of Endocrinology and Metabolism

Research Institute for Endocrine Sciences

e-ISSN 1726-9148
p-ISSN 1726-913X
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Cover image of the article: Body Mass Index in Turner Syndrome Before and After Growth Hormone Therapy

Image Credit:Int J Endocrinol Metab

Outline

Body Mass Index in Turner Syndrome Before and After Growth Hormone Therapy

Authors

Vakili Ra,*
*Corresponding Author: Emarn-Reza Hospital, P.O. Box 91735.-348, r-vakili@murns.ac.ir, IR Iran. Email: r-vakili@murns.ac.ir
International Journal of Endocrinology and Metabolism:Vol. 2, issue 2; 78-81
Published online:Jan 01, 2004
Article type:Research Article
How to Cite:R V. Body Mass Index in Turner Syndrome Before and After Growth Hormone Therapy. Int J Endocrinol Metab. 2004;2(2):. doi:

Abstract

Introduction:

Turner syndrome is the most common chromosomal abnormality in females. Girls with Turner syndrome have an abmormal or missing X choromosme that causes short stature, ovarian failure, renovascular and cardiac anomalies. It has been shown that there is a tendency to obesity in the Turner syndrome. This prospective study has been done to evaluate whether body mass index (BMI) is different in girls with Turner syndrome as compared to normal girls and also whether it is affected by growth hormone (GH) therapy.

Materials and Methods:

Materials and methods: BMI (kg/m2) was calculated for 21 girls with Turner syndrome at baseline (at the diagnosis), and after 6 months treatement with GH D.l IUJkglday subcutaneously at bedtime. The results were analyzed with the SPSS and the statistical significance was established at a p<0.05.

Results:

The mean age at diagnosis was 1l.22.9 years. Height and weight were reduced in Turner syndrome as compared to those of normal girls. BMI's was 18.443.32 and 18.784.21 kglm2 before and after 6-month period of GH therapy, respectively. No significant change in BMI was observed (p=0.334).

Conclusions:

Conclusion: This study documented that shortterm hGH administration was not associated with changes in BMI in girls with Turner syndrome.

Highlights

KeywordsTurner syndromeBody mass indexGrowth hormone

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Copyright

© 2004, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.

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