Clinical and Echocardiographic Evaluation of Regional Systolic Function Detected by Tissue Doppler Imaging in Hypertrophic Cardiomyopathy

M  Kiavar; N  Behzadnia; Anita Sadeghpour; Sh  Maddadi

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The Official Annually Journal of Cardiovascular Research Center, Shiraz University of Medical Sciences

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Clinical and Echocardiographic Evaluation of Regional Systolic Function Detected by Tissue Doppler Imaging in Hypertrophic Cardiomyopathy

Author(s):

M Kiavar¹,

N Behzadnia¹,

Anita Sadeghpour^1,*,

Sh Maddadi¹

1Shaheed Rajaie Cardiovascular Medical and Research Center, Tehran, Iran

International Cardiovascular Research Journal:Vol. 3, issue 3; e68032

Published online:Sep 30, 2009

Article type:Research Article

Received:Mar 07, 2018

Accepted:Sep 30, 2009

How to Cite:Kiavar M, Behzadnia N, Sadeghpour A, Maddadi S. Clinical and Echocardiographic Evaluation of Regional Systolic Function Detected by Tissue Doppler Imaging in Hypertrophic Cardiomyopathy. Int Cardiovasc Res J. 2009;3(3):e68032. doi:

Abstract

Background: Hypertrophic cardiomyopathy (HCM) is the most common type of the genetic cardiovascular
diseases. Regarding to tremendous heterogeneity in the phenotypic expression of HCM, which is generally unrelated
to genotype, we aimed to study, clinical and echocardiographic parameters such as Tissue Doppler Imaging
(TDI) in various subtypes of HCM patients and evaluate the influence of race and gender in Iranian patients.
Methods: Patients with HCM underwent a complete clinical and echocardiographic study including TDI to
assess regional systolic contraction( in the 12 segments ) and early diastolic annular velocity (Em) from the
septal mitral annulus.
Results: The study comprised 41 patients (20 women, mean age = 41 ± 15 years) with mean LVEF 55%±4.8%
and mean maximal septal thickness 2.07cm. Considering LVOT gradient>30mmHg, hypertrophic obstructive
cardiomyopathy (HOCM) was found in 18 (45%). Asymmetric septal hypertrophy (ASH) existed in 27 patients
(67%), systolic anterior motion of anterior mitral leaflet (SAM) in 25 persons (64%). Nineteen patients (46.3%)
were included in NYHA function class (FC) II and 6 (14.7%) in FC III or higher. We found syncope in 10
(24.4%), chest pain in 4 (9.8%), atrial fibrilation in 14.6 % and ventricular arrhythmias in (17.1%) of patients.
History of ICD was seen in 7 (17.1%) and PPM in 9 cases. Mean E’ velocity was 5.44± 1.65 cm/sec and S velocity
5.70± 1.49 cm/sec with significant lower S velocity and E’ in syncope patients. Overall, HOCM patients had
grade II diastolic dysfunction with E/É >15(17.54±7.46). Majority (25) of cases (61%) were categorized in type
III of HCM. RV involvement was observed in 11 patients (28.2%).No significant differences existed between
prevalence of syncope and dysrhythmia among HCM and HOCM patients.
Conclusion: In our study, we found lower detection of latent HOCM, compared to other studies, suggestive of
inadequate use of appropriate provocative maneuvers such as exercise stress echocardiography and amyl nitrate.
We detected remarkably lower S velocity (5.70± 1.49 cm/sec) and E’ velocity (5.44± 1.65 cm/sec) in HCM patients
compared to normal subjects, with more significant reductions in patients with syncope.

Keywords

Hypertrophic cardiomyopathy

Echocardiography

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References

1.
The references are available in PDF.

Left Ventricular Systolic Dyssynchrony in Patients with Hypertrophic Cardiomyopathy: The prevalence and its Relation to Syncope

A Sadeghpour,

M Kyavar,

N Behzadnia,

Sh Maddadi,

M Parsaei,

M Maleki

,et al.

Sadeghpour A, Kyavar M, Behzadnia N, Maddadi S, Parsaei M, et al. Left Ventricular Systolic Dyssynchrony in Patients with Hypertrophic Cardiomyopathy: The prevalence and its Relation to Syncope. Int Cardiovasc Res J. 2017;4(4):e58475. doi:

31

Dec

2022

Predictors and Prognosis of End-Stage Hypertrophic Cardiomyopathy

Mohammad Ali Sadr Ameli,

Azin Alizadehasl,

Sheida Keshavari,

Zohre Rahbar,

Mahdi Khalili,

Sepehr Jamalkhani

,et al.

Sadr Ameli MA, Alizadehasl A, Keshavari S, Rahbar Z, Khalili M, et al. Predictors and Prognosis of End-Stage Hypertrophic Cardiomyopathy. Int Cardiovasc Res J. 2022;16(4):e130190. doi:

17

May

2007

Diagnostic validity of electrocardiography compared with echocardiography for diagnosing left ventricular hypertrophy in patients with β- thalassemia major

Noormohammad Noori,

SH Rajaei

Noori N, Rajaei S. Diagnostic validity of electrocardiography compared with echocardiography for diagnosing left ventricular hypertrophy in patients with β- thalassemia major. Zahedan J Res Med Sci. 2007;9(2):e94810. doi:

1

Jun

2019

Could Mitral Valve and Mitral Annular Velocities, Left Atrial and Left Ventricular Wall Strain Predict the Presence of Coronary Artery Disease? A Case-Control Echocardiographic Study

Sasan Afifi,

Firoozeh Abtahi,

Aida Yoosefi,

Gholam Reza Rezaian

Afifi S, Abtahi F, Yoosefi A, Rezaian GR. Could Mitral Valve and Mitral Annular Velocities, Left Atrial and Left Ventricular Wall Strain Predict the Presence of Coronary Artery Disease? A Case-Control Echocardiographic Study. Int Cardiovasc Res J. 2019;13(2):e89149. doi:

1

Mar

2018

Cardiac Involvements in Patients with Celiac Disease by Doppler Tissue Echocardiography compared to Conventional Echocardiography

Noormohammad Noori,

Turan Shahraki,

Alireza Teimouri,

Iraj Shahramian

Noori N, Shahraki T, Teimouri A, Shahramian I. Cardiac Involvements in Patients with Celiac Disease by Doppler Tissue Echocardiography compared to Conventional Echocardiography. Int Cardiovasc Res J. 2018;12(1):e9976. doi:

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Author(s):

M Kiavar:[PubMed][Scholar]
N Behzadnia:[PubMed][Scholar]
Anita Sadeghpour:[PubMed][Scholar]
Sh Maddadi:[PubMed][Scholar]

The Official Annually Journal of Cardiovascular Research Center, Shiraz University of Medical Sciences

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Clinical and Echocardiographic Evaluation of Regional Systolic Function Detected by Tissue Doppler Imaging in Hypertrophic Cardiomyopathy

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