Molecular Epidemiology of Respiratory Viral Pathogens in Children with Asthma Exacerbations Admitted to Dr. Masih Daneshvari Hospital

2Pediatric Respiratory Disease Research Center, NRITLD, Masih Daneshvari Hospital, Shahid Beheshti University of Medical Sciences, [email protected], Iran

Journal of Comprehensive Pediatrics:Vol. 2, issue 2; 58-64

Published online:Dec 31, 2010

Article type:Research Article

Received:Feb 01, 2009

Accepted:Dec 01, 2010

How to Cite:Khalilzadeh S, Boloorsaz M, Nadji SA, Mahdaviani SA, Baghaie N, et al. Molecular Epidemiology of Respiratory Viral Pathogens in Children with Asthma Exacerbations Admitted to Dr. Masih Daneshvari Hospital. J Compr Ped. 2010;2(2):. doi:

Abstract

Background and Aim: A mortality rate of four million children from Acute Respiratory Infections (ARI) is reported for developing countries. This study aimed to clarify viral etiologies, clinical manifestations, and other contributing factors (e.g. age, sex, seasonal distribution) of ARIs in referrals to Masih Daneshvari hospital, the research center for pediatric respiratory diseases in Iran.

Materials and Methods: Clinical samples, including nasopharyngeal swabs and nasal washings, were collected from 50 exacerbated asthma cases between October 2007 and September 2008. The specimens were collected from children aged less than 17 years old who were admitted to Masih Daneshvari Hospital, NRITLD, Tehran. Diagnosis was performed by nested or Real time PCR on specimens using DNA and RNA extracted with Invite Spin DNA and Invite Spin RNA Mini Kits, respectively.

Results: The 50 participating patients included 14 girls and 36 boys. The most common age group was 6-11 years, followed by 1-6 years. Cough and wheezing were the most commonly reported symptoms and signs, respectively. Rhinovirus was the most common causative agent. The most common season for infection was autumn, followed by winter, with a total rate of 78% under the category “cold season.”

Conclusion: Considering the small sample size, it would be advisable to perform a multidisciplinary survey over the country to obtain sufficient data to generalize the results and to help the health care system make suitable decisions regarding viral infection prevention and control, especially for respiratory tract infections.

Keywords

Asthma

Children

Viral respiratory infections

Full Text

Full text is available in PDF

Prevalence of Respiratory Viral Infections in Children with Asthma in Kermanshah

Farhad Babaei,

Hamid Reza Mortazavi,

Nasim Kondori,

Bahareh Cheshmenooshi,

Mohsen Moghoofei

Babaei F, Mortazavi HR, Kondori N, Cheshmenooshi B, Moghoofei M. Prevalence of Respiratory Viral Infections in Children with Asthma in Kermanshah. Jundishapur J Microbiol. 2021;14(1):e100101. doi: https://doi.org/10.5812/jjm.100101

20

Jul

2023

Respiratory Viral Infections Among Children Hospitalized in a Great Referral Hospital in Iran During the Coronavirus Pandemic

Maryam Zendehrouh,

Abdollah Karimi,

Leila Azimi

Zendehrouh M, Karimi A, Azimi L. Respiratory Viral Infections Among Children Hospitalized in a Great Referral Hospital in Iran During the Coronavirus Pandemic. Arch Pediatr Infect Dis. 2023;11(3):e136943. doi: https://doi.org/10.5812/pedinfect-136943

18

Feb

2018

Human Metapneumovirus and Influenza Viruses in Children with Severe Acute Respiratory Infections in Iran

Jila Yavarian,

Nazanin Zahra Shafiei-Jandaghi,

Abbas Rahimi-Foroushani,

Azadeh Shadab,

Masoumeh Ghamarchehreh,

Talat Mokhtari-Azad

Yavarian J, Zahra Shafiei-Jandaghi N, Rahimi-Foroushani A, Shadab A, Ghamarchehreh M, et al. Human Metapneumovirus and Influenza Viruses in Children with Severe Acute Respiratory Infections in Iran. Inn J Pediatr. 2018;28(1):e60948. doi: https://doi.org/10.5812/ijp.60948

24

Oct

2014

Detection of Adenovirus Infection Among Children With Acute Respiratory Disease During 2010-2012 in Shiraz, Iran

Afagh Moattari,

Amir Emami,

Neda Pirbonyeh,

Ramin Yaghoobi

Moattari A, Emami A, Pirbonyeh N, Yaghoobi R. Detection of Adenovirus Infection Among Children With Acute Respiratory Disease During 2010-2012 in Shiraz, Iran. Arch Pediatr Infect Dis. 2014;2(4):e15930. doi: https://doi.org/10.5812/pedinfect.15930

30

Jul

2025

Prevalence, Management, and Treatment of Pediatric Acute Asthma in the Emergency Department: A Descriptive Cross-sectional Study in Zahedan, Iran (2023)

Zahra Shahraki Ghadimi,

Aghil Miri,

Zahra Assadi,

Mahdi Mohammadi,

Alireza Teimouri

Shahraki Ghadimi Z, Miri A, Assadi Z, Mohammadi M, Teimouri A. Prevalence, Management, and Treatment of Pediatric Acute Asthma in the Emergency Department: A Descriptive Cross-sectional Study in Zahedan, Iran (2023). Zahedan J Res Med Sci. 2025;27(4):e162520. doi: https://doi.org/10.5812/zjrms-162520

Import into EndNote Import into BibTex

Share on

Comments

Number of Comments:0

Cited by

Scopus by DOI: 0
Last Update: 2 weeks ago
Scopus by Title: 0
Last Update: 2 weeks ago
Scopus by Title (Ref): 4
Last Update: 2 weeks ago
CrossRef: 0
Last Update: 2 days ago

Metrics

Ordering Reprints

Articles are published under the Creative Commons license stated on each article. No permission or royalty fee is required for uses permitted by that license. CCC handles optional bulk and customized reprint orders. Any quotation covers production and delivery services only, not copyright permission. > Request Reprints from CCC

Search Relations

Author(s):

Soheila Khalilzadeh:[PubMed][Scholar]
Mohammad Boloorsaz:[PubMed][Scholar]
Syed Ali Nadji:[PubMed][Scholar]
Syed Ali Mahdaviani:[PubMed][Scholar]
Nooshin Baghaie:[PubMed][Scholar]
Maryam Hassanzad:[PubMed][Scholar]
Ali Velayati:[PubMed][Scholar]

Outlines

Molecular Epidemiology of Respiratory Viral Pathogens in Children with Asthma Exacerbations Admitted to Dr. Masih Daneshvari Hospital

Abstract

Full Text

Similar Articles

Prevalence of Respiratory Viral Infections in Children with Asthma in Kermanshah

Respiratory Viral Infections Among Children Hospitalized in a Great Referral Hospital in Iran During the Coronavirus Pandemic

Human Metapneumovirus and Influenza Viruses in Children with Severe Acute Respiratory Infections in Iran

Detection of Adenovirus Infection Among Children With Acute Respiratory Disease During 2010-2012 in Shiraz, Iran

Prevalence, Management, and Treatment of Pediatric Acute Asthma in the Emergency Department: A Descriptive Cross-sectional Study in Zahedan, Iran (2023)

Last Update: 2 weeks ago

Last Update: 2 weeks ago

Last Update: 2 weeks ago

Last Update: 2 days ago