Comparison of indomethacin suppository with intramuscular pethedine on the pain after cesarean section

¯Abstract Background: Management of the pain after cesarean section brings comfort for patient, in addition reduces cost and duration of hospitalization. Objective: This study was done compare indomethacin suppository with intramuscular pethedine on post operative pain. The used method for anesthesia in these patients was spinal anesthesia. Methods: In this double-blind clinical trial, 130 pregnant women from October 2001 to February 2002 in Kosar hospital were selected. All of them were operated under spinal anesthesia. Patients were divided randomly into two groups. In suppository group after operation 50 mg rectal suppository was used and every 6 hours was repeated for 12 hours. If pain was sever, 25 mg intramuscular pethedine was used. In pethedine group, after operation 25 mg pethedine was used and if pain was sever, this injection was repeated. Primary information include age, weight, parity, time and amount of pethedine, nausea and abdominal distention recorded. Two groups were compared by T-test and Chi-square. Findings: Two groups were similar in the view of age, weight, parity, and cause of cesarean. In suppositiry, 100 mg pethedine was used, but in pethedine group 2525 mg pethedine was used, that a significant difference was shown (P=0.000). In first group 12.3% and in second group 70.8% of patients had nausea, also 6.2% (in first group) and 53.8% (in second group) of patients had abdominal distention that between them there were a significant difference (P=0.000). Conclusion: Indomethacin suppository is a good analgesic and has less complications than pethedine for control of pain after cesarean section.