Comparison of Hashimoto thyroiditis in patients with type 1 diabetes and controls

F Saffari; A Asgari; T Sadeghi; F hajmanocheri

Journal of Inflammatory Diseases

The Official Journal of Qazvin University of Medical Sciences

Home

Instructions

Authors Guide Submit Manuscript

Outlines

Abstract
Copyright

Comparison of Hashimoto thyroiditis in patients with type 1 diabetes and controls

Author(s):

F Saffari^1,*,

A Asgari¹,

T Sadeghi²,

F hajmanocheri¹

1Qazvin University of Medical Sciences, Qazvin, Iran

2TUMS, Tehran, Iran

Journal of Inflammatory Diseases:Vol. 15, issue 2; 86-93

Published online:Sep 30, 2011

Article type:Research Article

How to Cite:Saffari F, Asgari A, Sadeghi T, hajmanocheri F. Comparison of Hashimoto thyroiditis in patients with type 1 diabetes and controls. J Inflamm Dis. 2024;15(2):e155620. doi:

Abstract

Background: Type 1 diabetes is the most common metabolic disease worldwide. Thyroid autoimmune diseases is the most common endocrinopathy in diabetes type 1 .Therefore, assessment of thyroid function tests and anti thyroid antibodies in diabetic patients (type 1) is beneficial in early. Objective: The purpose of this study was to compare the anti-thyroid antibodies in diabetic children (type 1) with healthy children . Methods: In this descriptive-analytic study, 65 children with Type 1 diabetes and 65 healthy children who had referred to Children's Hospital in Qazvin were selected by simple sampling. Anti-TG, Anti-TPO, TSH and T4 were measured in both groups. Chi-square, t-independent and Kruskal Valis was used for statistical analysis. Findings: The difference between sex and age in both groups (case and control) was not significant but BMI percentile was significantly different. Positive Anti-TG was 10.8% in patients and was 1.5% in controls .The difference was statistically significant (p=0.029). 16.9% of patients and 3.1% of controls had positive Anti-TPO (p=0.024).10.8% of patients had increased TSH and decreased T4 level (Overt Hypothyroidism) .4.6% of controls had increased TSH and normal T4 level (Subclinical Hypothyroidism). The difference was statistically significant for T4. Conclusion: It seems that the prevalence of Hashimoto thyroiditis in patients with type 1 diabetes is more than healthy people. Hence, evaluation of thyroid function tests (TFT) and antithyroid antibodies (Anti-TPO) is necessary to diagnosis and treatment of autoimmune thyroid disorders.

Keywords

Type 1 diabetes

Hashimoto thyroiditis

anti-thyroid antibodies

Anti-TG

Anti TPO

Hypothyroidism and type 1 diabetes mellitus

H Sheikholeslami,

A Ziaee,

S Darvishghaderi,

S Vahedi

Sheikholeslami H, Ziaee A, Darvishghaderi S, Vahedi S. Hypothyroidism and type 1 diabetes mellitus. J Inflamm Dis. 2024;11(3):e155344. doi:

19

May

2024

Insulin Resistance Among Children and Adolescents with Subclinical Hypothyroidism: A Case-Control Study

Homa Ilkhanipoor,

Negar Yazdani,

Hadis Ebrahimzade,

Hossein Moravej,

Zohreh Karamizadeh,

Anis Amirhakimi

Ilkhanipoor H, Yazdani N, Ebrahimzade H, Moravej H, Karamizadeh Z, et al. Insulin Resistance Among Children and Adolescents with Subclinical Hypothyroidism: A Case-Control Study. Health Scope. 2024;13(2):e143334. doi: https://doi.org/10.5812/healthscope-143334

4

May

2026

Microalbuminuria in Pediatric Autoimmune Thyroid Disease: A Preliminary Study

Yavuz Ozer,

Dilek Bingol Aydın,

Olcay Evliyaoglu

Ozer Y, Bingol Aydın D, Evliyaoglu O. Microalbuminuria in Pediatric Autoimmune Thyroid Disease: A Preliminary Study. Inn J Pediatr. 2026;In Press(In Press):e168189. doi: https://doi.org/10.5812/ijpediatr-168189

9

Dec

2019

Prevalence of Celiac Disease in Children with Type 1 Diabetes Mellitus in the South of Turkey

Yasin Sahin,

Meltem Didem Cakir,

Mehmet Isakoca,

Derya Aydin Sahin

Sahin Y, Cakir MD, Isakoca M, Aydin Sahin D. Prevalence of Celiac Disease in Children with Type 1 Diabetes Mellitus in the South of Turkey. Inn J Pediatr. 2019;30(1):e97306. doi: https://doi.org/10.5812/ijp.97306

30

Sep

2021

High Frequency of Nephropathy Among the Iranian Children and Adolescents With Type 1 Diabetes

Banafsheh Arad,

Victoria Chegini,

Hoda Hasani,

Ali Homaei,

Fatemeh Saffari

Arad B, Chegini V, Hasani H, Homaei A, Saffari F. High Frequency of Nephropathy Among the Iranian Children and Adolescents With Type 1 Diabetes. J Inflamm Dis. 2024;25(2):e156280. doi:

Import into EndNote Import into BibTex

Share on

Comments

Number of Comments:0

Cited by

Scopus by DOI: 0
Last Update: 2 weeks ago
Scopus by Title: 0
Last Update: 2 weeks ago
Scopus by Title (Ref): 0
Last Update: 2 weeks ago
CrossRef: 0
Last Update: 1 day ago

Metrics

Ordering Reprints

Articles are published under the Creative Commons license stated on each article. No permission or royalty fee is required for uses permitted by that license. CCC handles optional bulk and customized reprint orders. Any quotation covers production and delivery services only, not copyright permission. > Request Reprints from CCC

Search Relations

Author(s):

F Saffari:[PubMed][Scholar]
A Asgari:[PubMed][Scholar]
T Sadeghi:[PubMed][Scholar]
F hajmanocheri:[PubMed][Scholar]

The Official Journal of Qazvin University of Medical Sciences

Outlines

Comparison of Hashimoto thyroiditis in patients with type 1 diabetes and controls

Abstract

Similar Articles

Hypothyroidism and type 1 diabetes mellitus

Insulin Resistance Among Children and Adolescents with Subclinical Hypothyroidism: A Case-Control Study

Microalbuminuria in Pediatric Autoimmune Thyroid Disease: A Preliminary Study

Prevalence of Celiac Disease in Children with Type 1 Diabetes Mellitus in the South of Turkey

High Frequency of Nephropathy Among the Iranian Children and Adolescents With Type 1 Diabetes

Last Update: 2 weeks ago

Last Update: 2 weeks ago

Last Update: 2 weeks ago

Last Update: 1 day ago