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Jundishapur Journal of Microbiology
Ahvaz Jundishapur University of Medical Sciences
e-ISSN 2008-4161
p-ISSN 2008-3645
Antifungal activity of Satureja khuzestanica (Jamzad) leaves extracts
Authors
1Department of Parasitology and Mycology, Medical School, Ahvaz Jundishapur University of Medical Sciences, Iran
2Department of Parasitology and Mycology, Medical School, Ahvaz Jundishapur University of Medical Sciences, mjzarrin@yahoo.co.uk, Iran
*Corresponding Author: Department of Parasitology and Mycology, Medical School, Ahvaz Jundishapur University of Medical Sciences, mjzarrin@yahoo.co.uk, Iran. Email: mjzarrin@yahoo.co.uk
Published online:Jan 31, 2010
Article type:Research Article
Received:Nov 01, 2009
Accepted:Jan 01, 2010
How to Cite:Sadeghi-Nejad B, Shiravi F, Ghanbari S, Alinejadi M, Zarrin M. Antifungal activity of Satureja khuzestanica (Jamzad) leaves extracts. Jundishapur J Microbiol. 2010;3(1):. doi:
Abstract
Introduction and objective: Opportunistic fungal infections have been a common cause of morbidity and mortality in the immunosupresed individuals such as AIDS and organ recipients. Treatment of these infections is a great challenge, thus antifungal therapy is playing a greater role in their health care. Traditional plants are a valuable source of novel antifungals. The aim of this study was to assess in vitro antifungal activity of the ethanolic extract of Satureja khuzestanica leaves.
Materials and methods: In the current experimental study the Minimum Inhibitory Concentration (MIC) of the ethanolic extract of S. khuzestanica leaves was evaluated against saprophytic fungi isolates such as Aspergillus flavus, A. niger, Penicillium sp., Fusarium sp., Alternaria sp., Rhizopus sp., and Mucor sp. Antifungal susceptibilities were determined using the agar well diffusion method and amphotericine B was used as positive control as gold therapeutic agent.
Results: Our findings showed that the ethanolic extract of S. khuzestanica leaves exhibited antifungal activity against all tested saprophytic fungi with MIC values (625-5000µg/ml).
Conclusion: The Results demonstrated that this plant has strong antifungal potential against all tested fungi.
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Copyright
© 2010, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.
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