Journal of Kermanshah University of Medical Sciences
Peer-reviewed Medical Quarterly
Outlines
Autoimmune thyroid disorder in patient with chronic hepatitis C before treatment
Author(s):
Mehr Ali Rahimi1, Babak Sayad2, Ahmad Tahamoli Roudsari3,*, Karoun Shahebrahimi1, Maria Shirvani4, Mansour Rezaei51Dept of Internal Medicine, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran
2Dept. of Infectious Medicine, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran
3Student Research Committee, Kermanshah University of Medical Sciences, Kermanshah, Iran
4Hepatitis Research Center, Emam Reza Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran
5Dept. of Biostatistics and Epidemiology, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran
*Corresponding Author: Corresponding author: Ahmad Tahamoli Roudsari, Student Research Committee, Kermanshah University of Medical Sciences, Kermanshah, Iran, Tel: +98 831 4276300 Email: [email protected]
Published online:Sep 19, 2011
Article type:Research Article
Received:May 15, 2010
Accepted:Oct 05, 2010
How to Cite:Rahimi MA, Sayad B, Tahamoli Roudsari A, Shahebrahimi K, Shirvani M, et al. Autoimmune thyroid disorder in patient with chronic hepatitis C before treatment. J Kermanshah Univ Med Sci. 2011;15(3):e79361. doi:
Abstract
Background: Creating autoantibodies against thyroid in hepatitis C patients who are being treated with interferon is now recognized for several years. Recently, some studies have claimed that prevalence of autoimmune thyroid disorders in Hepatitis C patients is higher when they are not treated by interferon and/or at the beginning of diagnosis, however the area still remained controversial. In order to analyze autoimmune thyroid disorders in Hepatitis C patients who are not still treated by interferon and compare them with the control group this study has been conducted.
Methods: A Case-Control study including 86 chronic hepatitis C patients before commencing treatment by interferon and 86 healthy volunteer individuals were examined. Data was collected using demographic and clinical variables questionnaires from both groups. FT4, TSH, Anti TPO and Anti TG examinations carried out in both group.
Results: The findings of this study showed increase Anti TPO in 4 cases in 13 case, increased is Anti TG in 5 case, sub clinical hypothyroid, ism sub clinical hyperthyroid in 3 ism and hyperthyroid ism in one case in the case group were observed. There was no significant difference between the case and the control group.
Conclusion: We can conclude that there is no relationship between chronic hepatitis C infection and autoimmune thyroid.
References
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Copyright
© 2011, Journal of Kermanshah University of Medical Sciences. This open-access article is available under the Creative Commons Attribution-NonCommercial 4.0 (CC BY-NC 4.0) International License (https://creativecommons.org/licenses/by-nc/4.0/), which allows for the copying and redistribution of the material only for noncommercial purposes, provided that the original work is properly cited.
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