Koomesh
Journal of Semnan University of Medical Sciences
Outlines
Effects of Ziziphus jujube Mill., Cynara scolymus L. and and Cichorium intybus L. combination extract on non-alcoholic fatty liver disease in rats
Abstract
References
- 1.Chan DF, Li AM, Chu WC, Chan MH, Wong EM, Liu EK. Hepatic steatosis in obese Chinese children. Int J Obes Relat Metab Disord 2004; 28: 1257-1263.
- 2.Guijarro de Armas MG, Monereo MS, Navea AC, Merino VM, Vega Pinero MB. Non-alcoholic fatty liver in children and adolescents with excess weight and obesity. Med Clin (Barc) 2015; 144: 55-58.
- 3.Kitade H, Chen G, Ni Y, Ota T. Nonalcoholic Fatty Liver Disease and Insulin Resistance: New Insights and Potential New Treatments. Nutrients 2017; 9: 387.
- 4.Gungor N, Saad R, Janosky J, Arslanian S. Validation of surrogate estimates of insulin sensitivity and insulin secretion in children and adolescents. J Pediatr 2004; 144: 47-55.
- 5.Xanthakos S, Miles L, Bucuvalas J, Daniels S, Garcia V, Inge T. Histologic spectrum of nonalcoholic fatty liver disease in morbidly obese adolescents. Clin Gastroenterol Hepatol 2006; 4: 226-232.
- 6.Vajro P, Lenta S, Socha P, Dhawan A, McKiernan P, Baumann U. Diagnosis of nonalcoholic fatty liver disease in children and adolescents: position paper of the ESPGHAN Hepatology committee. J Pediatr Gastroenterol Nutr 2012; 54: 700-713.
- 7.Al-Reza SM, Yoon JI, Kim HJ, Kim JS, Kang SC. Anti-inflammatory activity of seed essential oil from Zizyphus jujuba. Food Chem Toxicol 2010; 48: 639-43.
- 8.Cheng G, Bai Y, Zhao Y, Tao J, Liu Y, Tu G, et al. Flavonoids from Ziziphus jujuba Mill var. spinosa. Tetrahedron 2000; 56: 8915-8920.
- 9.Shen X, Tang Y, Yang R, Yu L, Fang T, Duan Ja. The protective effect of Zizyphus jujube fruit on carbon tetrachloride-induced hepatic injury in mice by anti-oxidative activities. J Ethnopharmacology 2009; 122: 555-560.
- 10.Zhao HX, Zhang HS, Yang SF. Phenolic compounds and its antioxidant activities in ethanolic extracts from seven cultivars of Chinese jujube. Food Sci Hum Well 2014; 3: 183-190.
- 11.Lpez-Molina D, Navarro-Martnez MD, Rojas-Melgarejo F, Hiner AN, Chazarra S, Rodrguez-Lpez JN. Molecular properties and prebiotic effect of inulin obtained from artichoke (Cynara scolymus L.). Phytochemistry 2005; 66: 1476-1484.
- 12.Rodriguez TS, Gimnez DG, De la Puerta Vzquez R. Choleretic activity and biliary elimination of lipids and bile acids induced by an artichoke leaf extract in rats. Phytomedicine 2002; 9: 687-693.
- 13.Abd el Azeem E, Alaa B, Zakaria Z. Anti-obesity and anti-fatty liver effects of Cynara scolymus L. leaf extract in mice under diet-induced obesity. Int J Biochem Res Rev 2016; 11(1): 1-11.
- 14.Zafar R, Ali SM. Anti-hepatotoxic effects of root and root callus extracts of Cichorium intybus L. J Ethnopharmacology 1998; 63: 227-231.
- 15.Hassan HA, Yousef MI. Ameliorating effect of chicory (Cichorium intybus L.)-supplemented diet against nitrosamine precursors-induced liver injury and oxidative stress in male rats. Food Chem Toxicol 2010; 48: 2163-2169.
- 16.El-Sayed YS, Lebda MA, Hassinin M, Neoman SA. Chicory (Cichorium intybus L.) root extract regulates the oxidative status and antioxidant gene transcripts in CCl 4-induced hepatotoxicity. PLoS One 2015; 10: e0121549.
- 17.Emamat H, Noori M, Foroughi F, Rismanchi M, Eini-Zinab H, Hekmatdoost A. An accessible and pragmatic experimental model of nonalcoholic fatty liver disease. Middle East J Dig Dis 2016; 8: 109-115.
- 18.Haghi G, Hatami A, Arshi R. Distribution of caffeic acid derivatives in Gundelia tournefortii L. Food Chem 2011; 124: 1029-1035.
- 19.Abbas ZK, Saggu S, Sakeran MI, Zidan N, Rehman H, Ansari AA. Phytochemical, antioxidant and mineral composition of hydroalcoholic extract of chicory (Cichorium intybus L.) leaves. Saudi J Biol Sci 2015; 22: 322-326.
- 20.Ahmed U, Redgrave TG, Oates PS. Effect of dietary fat to produce non-alcoholic fatty liver in the rat. J Gastroenterol Hepatol 2009; 24: 1463-1471.
- 21.Kim HS. Effects of the Zizyphus jujuba seed extract on the lipid components in hyperlipidemic rats. J Food Sci Nutr 2002; 7: 72-77.
- 22.Peng WH, Hsieh MT, Lee YS, Lin YC, Liao J. Anxiolytic effect of seed of Ziziphus jujuba in mouse models of anxiety. J Ethnopharmacol 2000; 72: 435-441.
- 23.Yue Y, Wu S, Zhang H, Zhang X, Niu Y, Cao X, et al. Characterization and hepatoprotective effect of polysaccharides from Ziziphus jujuba Mill. var. spinosa (Bunge) Hu ex H. F. Chou sarcocarp. Food Chem Toxicol 2014; 74: 76-84.
- 24.Li JW, Fan LP, Ding SD, Ding XL. Nutritional composition of five cultivars of Chinese jujube. Food Chem 2007; 103: 454-460.
- 25.Fritsche J, Beindorff CM, Dachtler M, Zhang H, Lammers JG. Isolation, characterization and determination of minor artichoke (Cynara scolymus L.) leaf extract compounds. Eur Food Res Technol 2002; 215: 149-157.
- 26.Mocelin R, Marcon M, Santo GD, Zanatta L, Sachett A, Schnell AP, et al. Hypolipidemic and antiatherogenic effects of Cynara scolymus in cholesterol-fed rats. Revista Brasil Farmacogn 2016; 26: 233-239.
- 27.Heidarian E, Rafieian-Kopaei M. Protective effect of artichoke (Cynara scolymus) leaf extract against lead toxicity in rat. Pharm Biol 2013; 51: 1104-1109.
- 28.Rangboo V, Noroozi M, Zavoshy R, Rezadoost SA, Mohammadpoorasl A. The effect of artichoke leaf extract on alanine aminotransferase and aspartate aminotransferase in the patients with nonalcoholic steatohepatitis. Int J Hepatol 2016; 2016: 6.
- 29.Asl ZS, Malekirad AA, Abdollahi M, Bakhshipour A, Dastjerdi HA, Mostafalou S, Poor RY. Effects of the mixture of cichorium intybus L. and Cinnamomum zeylanicum on hepatic enzymes activity and biochemical parameters in patients with nonalcoholic fatty liver disease. Health 2014; 6: 1212.
Copyright
© 2018, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.
Similar Articles
Hepatoprotective Activity of Cichorium intybus L. Leaves Extract Against Carbon Tetrachloride Induced Toxicity
Jamshidzadeh A, Khoshnood MJ, Dehghani Z, Niknahad H. Hepatoprotective Activity of Cichorium intybus L. Leaves Extract Against Carbon Tetrachloride Induced Toxicity. Iran J Pharm Res. 2022;5(1):e128261. doi: https://doi.org/10.22037/ijpr.2010.651
Capparis spinosa Attenuates Hepatic Inflammation and Fibrosis by Suppressing Inflammatory Cytokines in a Wistar Rat Model of Nonalcoholic Steatohepatitis
Akbari R, Behdarvand T, Yaghooti H, Jalali MT, Mohammadtaghvaei N. Capparis spinosa Attenuates Hepatic Inflammation and Fibrosis by Suppressing Inflammatory Cytokines in a Wistar Rat Model of Nonalcoholic Steatohepatitis. Iran J Pharm Res. 2025;24(1):e166099. doi: https://doi.org/10.5812/ijpr-166099
Maternal Administration of Cichorium intybus L. Extract Decreases the Plasma Total and Conjugated Bilirubin Level in Rat Neonates
Naderi R, Hassanipour M, Aminzadeh F, Manshoori A, Shamsizadeh A, et al. Maternal Administration of Cichorium intybus L. Extract Decreases the Plasma Total and Conjugated Bilirubin Level in Rat Neonates. Jundishapur J Nat Pharm Prod. 2018;13(2):e14043. doi: https://doi.org/10.5812/jjnpp.14043
Evaluating the Efficacy of Carum Copticum Seeds on the Treatment of Patients with Nonalcoholic Fatty Liver Disease: A Multi-Center, Randomized, Triple–Blind, Placebo-Controlled Clinical Trial Study
Shafiezadeh R, Alavian SM, Namdar H, Gholami-Fesharaki M, Esmaeili SS. Evaluating the Efficacy of Carum Copticum Seeds on the Treatment of Patients with Nonalcoholic Fatty Liver Disease: A Multi-Center, Randomized, Triple–Blind, Placebo-Controlled Clinical Trial Study. Hepat Mon. 2020;20(12):e110488. doi: https://doi.org/10.5812/hepatmon.110488
Hepatoprotective Effects of a Combination of Three Medicinal Plants on Carbamazepine-Induced Liver Injury: A Case Report
Ebadollahi-Natanzi A, Arab-Rahmatipour G. Hepatoprotective Effects of a Combination of Three Medicinal Plants on Carbamazepine-Induced Liver Injury: A Case Report. Zahedan J Res Med Sci. 2026;28(3):e170006. doi: https://doi.org/10.5812/zjrms-170006
- Scopus by DOI: 0
Last Update: 0 months ago
- Scopus by Title: 3
Last Update: 0 months ago
- Scopus by Title (Ref): 3
Last Update: 0 months ago
- CrossRef: 0
Last Update: 3 days ago
Ordering Reprints
Articles are published under the Creative Commons license stated on each article. No permission or royalty fee is required for uses permitted by that license. CCC handles optional bulk and customized reprint orders. Any quotation covers production and delivery services only, not copyright permission. > Request Reprints from CCC
Author(s):