Shiraz E-Medical Journal
Salmonellosis is a major health problem, especially in developing countries like Rwanda. Salmonella typhi infects only human and human transmission occur through feaco-oral route. Moreover, species are becoming resistant to the commonly used antibiotics.
The aim of the present study is to know antimicrobial susceptibility patterns with special reference to multidrug resistance Salmonella enterica serovar Typhi and reduced susceptibility to nalidixic acid
A total 69 S.typhi isolated of King Faisal hospital, Kigali, Rwanda from stool and blood specimens were included in the study. Antimicrobial susceptibility was done by using Kirby-Bauer disc diffusion method.
There was decreased susceptibility was observed in Chloramphenicol, Ampicillin, Amoxycillin/Calvvlanic acid, Tetracycline, Cotrimoxazole and Nalidixic acid. These were sig-nificant increase in the multidrug resistant salmonella typhi (MRST) from 9.1% to 25% re-spectively between 2007 and 2008. All the isolates were 100% sensitive to Ceftriaxone, Levofloxacin and Ciprofloxacin
Typhoid fever has been endemic in Kigali. Decreased susceptibility towards nalidixic is obsevered which gives us alarm for treatment failure towards fluoroquinolones. The antibiotic sensitivity pattern is changing and resistant cases are emerging due to inap-propriate use of antibiotics.
© 2010, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.
Mandal S, DebMandal M, Pal N. Nalidixic acid susceptibility status of Salmonella enterica serovar Typhi isolates from Kolkata, India. Jundishapur J Microbiol. 2011;4(1):. doi:
Ma J, Li W, Liu J, Li M. Serotypes, Antibiotic Resistance Genes, and Salmonella Pathogenicity Island Genes of Salmonella from Patients in a Hospital in Weifang, China. Jundishapur J Microbiol. 2022;15(8):e128675. doi: https://doi.org/10.5812/jjm-128675
Nodeh Farahani N, Masjedian Jazi F, Nikmanesh B, Asadolahi P, Sadeghi Kalani B, et al. Prevalence and Antibiotic Susceptibility Patterns of Salmonella and Shigella Species Isolated from Pediatric Diarrhea in Tehran. Arch Pediatr Infect Dis. 2018;6(4):e57328. doi: https://doi.org/10.5812/pedinfect.57328
Helali-Pargali R, Ranjbar R, Memariani M, Najafi A, Mammina C. Molecular Characterization of Quinolone Resistance Determinants in Non-Typhoidal Salmonella Strains Isolated in Tehran, Iran. Jundishapur J Microbiol. 2022;15(5):e120766. doi: https://doi.org/10.5812/jjm-120766
Lertworapreecha M, Sutthimusik S, Tontikapong K. Antimicrobial Resistance in Salmonella enterica Isolated From Pork, Chicken, and Vegetables in Southern Thailand. Jundishapur J Microbiol. 2012;6(1):36-41. doi: https://doi.org/10.5812/jjm.4312
Ordering Reprints
Articles are published under the Creative Commons license stated on each article. No permission or royalty fee is required for uses permitted by that license. CCC handles optional bulk and customized reprint orders. Any quotation covers production and delivery services only, not copyright permission. > Request Reprints from CCC
Author(s):
