Full Text
Full text is available in PDF
Background:
Intra-articular analgesia is a pain reliever that is frequently administered following arthroscopic knee surgery.
e-ISSN 2228-7531
p-ISSN 2228-7523
Comparing the Efficacy of Intra-Articular Application of Morphine and Tramadol on Postoperative Pain After Arthroscopic Knee Surgery
Authors
1Akhtar Orthopedic Hospital, Shahid Beheshti University of Medical Sciences, Tehran, IR Iran
2Department of Anesthesiology, Akhtar Orthopedic Hospital, Shahid Beheshti University of Medical Sciences, faramarzmosaffa@yahoo.com, Tehran, IR Iran
*Corresponding Author: Department of Anesthesiology, Akhtar Orthopedic Hospital, Shahid Beheshti University of Medical Sciences, faramarzmosaffa@yahoo.com, Tehran, IR Iran. Email: faramarzmosaffa@yahoo.com
Published online:Jul 01, 2012
Article type:Research Article
Received:Mar 11, 2012
Accepted:May 08, 2012
Abstract
Objectives:
The purpose of this study was to compare the efficacy of intra-articular application\r\nof morphine and tramadol on postoperative pain after arthroscopic knee surgery
Patients and Methods:
For this randomized double blinded clinical trial, 132 patients\r\nundergoing minor arthroscopic knee surgery were randomly assigned to receive either;\r\n5 mg morphine or 50 mg tramadol intra-articularly. Pain was evaluated by means of the\r\nverbal pain rating score (VRS) preoperatively (at rest and on movement of the knee joint)\r\nand postoperatively at 0, 1, 2, 3, 4, 6, 12 and 24 hours. Meanwhile, the time of the first analgesic\r\nrequest and need for supplemental analgesic were also recorded.
Results:
There was no statistically significant difference in VRS scoring between the two\r\ngroups during the preoperative period either at rest or on knee movement. Meanwhile,\r\nVRS scores did not differ significantly between the morphine and tramadol treated\r\ngroups postoperatively, except for in the one-hour post-operative scores in which the\r\ntramadol-treated group experienced less pain (P < 0.007). Post-operative VRS scores at\r\n6, 12, and 24 hours were significantly decreased when compared with previous scores in\r\nboth morphine and tramadol prescribed subjects (P < 0.001), hence, both local analgesics\r\ncan significantly reduce pain after minor knee surgery.
Conclusions:
We have found a postoperative analgesic effect of intra-articularly administered\r\nmorphine and tramadol following minor arthroscopic knee surgeries with a\r\nmaximum effect 6 hours post injection.
Highlights
How to Cite:Jazayeri SM, Mosaffa F, Abbasian M, Hosseinzadeh HR. Comparing the Efficacy of Intra-Articular Application of Morphine and Tramadol on Postoperative Pain After Arthroscopic Knee Surgery. Anesth Pain Med. 2012;2(1):. doi: https://doi.org/10.5812/aapm.4815
Copyright
© 2012, Author(s). This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International License (CC BY 4.0) (https://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Similar Articles
22
Jun
2015
The Analgesic Effects of Morphine and Tramadol Added to Intra-articular Levobupivacaine-Tenoxicam Combination for Arthroscopic Knee Surgery on Postoperative Pain; a Randomized Clinical Trial
Ebru Gelici Oral,
Ayse Hanci,
Gulcihan Ulufer Sivrikaya,
Hale Dobrucali,
Leyla Turkoglu Kilinc
Oral EG, Hanci A, Ulufer Sivrikaya G, Dobrucali H, Turkoglu Kilinc L. The Analgesic Effects of Morphine and Tramadol Added to Intra-articular Levobupivacaine-Tenoxicam Combination for Arthroscopic Knee Surgery on Postoperative Pain; a Randomized Clinical Trial. Anesth Pain Med. 2015;5(3):e24047. doi: https://doi.org/10.5812/aapm.5(3)2015.24047
19
Feb
2015
The Effect of Intra-Articular Meperidine and Bupivacaine 0.5% on Postoperative Pain of Arthroscopic Knee Surgery; a Randomized Double Blind Clinical Trial
Farnad Imani,
Saeidreza Entezary,
Mohammad Razi,
Ali Akbar Jafarian,
Fardin Yousefshahi,
Hasan Etemadi
,et al.Imani F, Entezary S, Razi M, Jafarian AA, Yousefshahi F, et al. The Effect of Intra-Articular Meperidine and Bupivacaine 0.5% on Postoperative Pain of Arthroscopic Knee Surgery; a Randomized Double Blind Clinical Trial. Anesth Pain Med. 2015;5(1):e27470. doi: https://doi.org/10.5812/aapm.27470
18
Mar
2024
Comparing Apotel and Remifentanil for Multimodal Patient-Controlled Analgesia in Postoperative Pain Management Following Total Knee Arthroplasty Surgery: A Randomized Controlled Trial
Seyed Ali Golrokh Moghadam,
Amin Tajerian,
Behnam Mahmoudieh,
Mohsen Parsi Khamene,
Alireza Kamali
Golrokh Moghadam SA, Tajerian A, Mahmoudieh B, Parsi Khamene M, Kamali A. Comparing Apotel and Remifentanil for Multimodal Patient-Controlled Analgesia in Postoperative Pain Management Following Total Knee Arthroplasty Surgery: A Randomized Controlled Trial. Anesth Pain Med. 2024;14(2):e141975. doi: https://doi.org/10.5812/aapm-141975
6
Feb
2023
Comparison of Perioperative Pregabalin and Duloxetine for Pain Management After Total Knee Arthroplasty: A Double-Blind Clinical Trial
Farnad Imani,
Azadeh Emami,
Mahzad Alimian,
Nasim Nikoubakht,
Niloofar Khosravi,
Mehdi Rajabi
,et al.Imani F, Emami A, Alimian M, Nikoubakht N, Khosravi N, et al. Comparison of Perioperative Pregabalin and Duloxetine for Pain Management After Total Knee Arthroplasty: A Double-Blind Clinical Trial. Anesth Pain Med. 2023;13(1):e127017. doi: https://doi.org/10.5812/aapm-127017
23
Jul
2025
A Comparative Analysis of Bupivacaine Concentrations in Adductor Canal Block for Pain Management Post-unilateral Knee Arthroplasty
Hosnieh Esmaeili Nameghi,
Amir Shahriar Ariamanesh,
Mehrdad Mokarram Dori,
Vahideh Ghorani,
Malihe Aghasizadeh,
Seyed-Hossein Khademi
Esmaeili Nameghi H, Ariamanesh AS, Mokarram Dori M, Ghorani V, Aghasizadeh M, et al. A Comparative Analysis of Bupivacaine Concentrations in Adductor Canal Block for Pain Management Post-unilateral Knee Arthroplasty. Anesth Pain Med. 2025;15(4):e161215. doi: https://doi.org/10.5812/aapm-161215
Cited by
- Scopus by DOI: 10
Last Update: 1 month ago
- Scopus by Title: 10
Last Update: 1 month ago
- Scopus by Title (Ref): 10
Last Update: 1 month ago
- CrossRef: 4
Last Update: 5 days ago
- OpenAlex: 11
Last Update: 14 hours ago
- OpenCitations: 10
Last Update: 3 days ago
Comments
Number of Comments:0Indexed in
