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Background:
Intra-articular analgesia is a pain reliever that is frequently administered following arthroscopic knee surgery.
e-ISSN 2228-7531
p-ISSN 2228-7523
Comparing the Efficacy of Intra-Articular Application of Morphine and Tramadol on Postoperative Pain After Arthroscopic Knee Surgery
Authors
1Akhtar Orthopedic Hospital, Shahid Beheshti University of Medical Sciences, Tehran, IR Iran
2Department of Anesthesiology, Akhtar Orthopedic Hospital, Shahid Beheshti University of Medical Sciences, [email protected], Tehran, IR Iran
*Corresponding Author: Department of Anesthesiology, Akhtar Orthopedic Hospital, Shahid Beheshti University of Medical Sciences, [email protected], Tehran, IR Iran. Email: [email protected]
Published online:Jul 01, 2012
Article type:Research Article
Received:Mar 11, 2012
Accepted:May 08, 2012
How to Cite:Jazayeri SM, Mosaffa F, Abbasian M, Hosseinzadeh HR. Comparing the Efficacy of Intra-Articular Application of Morphine and Tramadol on Postoperative Pain After Arthroscopic Knee Surgery. Anesth Pain Med. 2012;2(1):. doi: https://doi.org/10.5812/aapm.4815
Abstract
Objectives:
The purpose of this study was to compare the efficacy of intra-articular application\r\nof morphine and tramadol on postoperative pain after arthroscopic knee surgery
Patients and Methods:
For this randomized double blinded clinical trial, 132 patients\r\nundergoing minor arthroscopic knee surgery were randomly assigned to receive either;\r\n5 mg morphine or 50 mg tramadol intra-articularly. Pain was evaluated by means of the\r\nverbal pain rating score (VRS) preoperatively (at rest and on movement of the knee joint)\r\nand postoperatively at 0, 1, 2, 3, 4, 6, 12 and 24 hours. Meanwhile, the time of the first analgesic\r\nrequest and need for supplemental analgesic were also recorded.
Results:
There was no statistically significant difference in VRS scoring between the two\r\ngroups during the preoperative period either at rest or on knee movement. Meanwhile,\r\nVRS scores did not differ significantly between the morphine and tramadol treated\r\ngroups postoperatively, except for in the one-hour post-operative scores in which the\r\ntramadol-treated group experienced less pain (P < 0.007). Post-operative VRS scores at\r\n6, 12, and 24 hours were significantly decreased when compared with previous scores in\r\nboth morphine and tramadol prescribed subjects (P < 0.001), hence, both local analgesics\r\ncan significantly reduce pain after minor knee surgery.
Conclusions:
We have found a postoperative analgesic effect of intra-articularly administered\r\nmorphine and tramadol following minor arthroscopic knee surgeries with a\r\nmaximum effect 6 hours post injection.
Copyright
© 2012, Author(s). The Author(s) retain copyright in the Article. Upon acceptance, the Author(s) grant Brieflands the non-exclusive right of first publication and a worldwide, perpetual, royalty-free, non-exclusive license to copyedit, format, publish, reproduce, distribute, display, preserve, archive, index, promote, and make the Version of Record available in all formats and media. Brieflands and the relevant journal will be identified as the original publisher of the Version of Record. The Article will be published under the [Creative Commons Attribution 4.0 International License (CC BY 4.0)](https://creativecommons.org/licenses/by/4.0/). The Author(s) may immediately deposit and share the Version of Record in any repository or platform. No separate permission or fee is required for uses permitted under CC BY 4.0. CCC may provide optional customized reprint services.
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