Biomechanical analysis of blast-induced traumatic brain injury

authors:

avatar Mohammad Hossein Lashkari 1 , avatar Ata Koohian 2 , avatar kambiz kangarloo 3 , *

Department of Surgery, AJA University of Medical Sciences, Tehran, Iran, Andorra
Department of Physics, University of Tehran, Tehran, Iran., Andorra
Postdoctoral Researcher, Department of Biomedical Engineering, Amirkabir University of Technology, Tehran, Iran., Andorra
Annals of Military and Health Sciences Research: Vol.12, issue 2; e63365
published online: February 20, 2014
article type: Original Article
received: August 14, 2013
accepted: January 16, 2014

how to cite: Lashkari M H , Koohian A , kangarloo K. Biomechanical analysis of blast-induced traumatic brain injury. Ann Mil Health Sci Res. 2014;12(2):e63365. 

Abstract

Materials and Methods: To investigate the mechanical response of human brain to blast waves and to identify the injury mechanisms of TBI, a three-dimensional finite elementhead model consisting of the scalp, skull, cerebrospinal fluid (CSF) and brain was developed from    the imaging data of a human head.The mechanical properties of brain tissue were obtained from  the literature.

Results: Throughout the loading regime, CSF acted as a protective layer for brain tissue by absorbing shear strain energy. Biomechanical loading of the brain was governed by direct wave transmission, structural deformations, and wave reflections from tissue-material interfaces.

Conclusion: The brain experiences a complex set of direct and indirect loadings emanating from different sources (reflections from tissue interfaces and skull deformation) at different points of time. The flow dynamics strongly depend on geometry (shape, curvature) and structure (flexural rigidity, thickness) of a specimen and should be considered in understanding biomechanical loading pattern.

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