https://doi.org/10.5812/pedinfect.4862

A case series report of Iranian children Hemophagocytic Lymphohistiocytosis syndrome

authors:

avatar Roxana M. Ghanaie 1 , avatar Reza Shiari 2 , avatar Abdollah Karimi 1 , * , avatar Shahnaz Armin 1 , avatar Alireza Fahimzad 1 , avatar Faride Shiva 1 , avatar Mohammad Taghi Arzanian 3

Pediatric Infections Research Center, Shahid Beheshti University of Medical Sciences, dr_akarimi@yahoo.com, IR Iran
Department of Pediatrics, Division of Pediatric Rheumatology, Mofid Children Hospital, Shahid Beheshti University of Medical Sciences, IR Iran
Department of Pediatrics, Division of Pediatric Oncology, Mofid Children Hospital, Shahid Beheshti University of Medical Sciences, IR Iran
Archives of Pediatric Infectious Diseases: Vol.1, issue 1; 31-35
published online: April 14, 2013
article type: Case Report
received: March 13, 2012
accepted: June 20, 2012

how to cite: Ghanaie R, Shiari R, Karimi A, Armin S, Fahimzad A, et al. A case series report of Iranian children Hemophagocytic Lymphohistiocytosis syndrome. Arch Pediatr Infect Dis. 2013;1(1): 31-35. https://doi.org/10.5812/pedinfect.4862.

Abstract

Hemophagocytic lymphohistiocytosis (HLH) is an aggressive and potentially life-threatening disease and has to be considered in the differential diagnosis of many conditions. HLH comprises two different conditions that are difficult to differentiate; Familial hemophagocytic lymphohistiocytosis (FHLH) or familial erythrophagocytic lymphohistiocytosis (FEL), and Secondary hemophagocytic syndromes (secondary HLH, sHLH). Herein, we report a case series of Iranian children with HLH and describe the symptoms and outcome of this disease in Iran.

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