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Urinary Antigen Test EIA: A Valuable Rapid Clinical Method for the Ddiagnosis of Legionella

Author(s):
Hossein GoudarziHossein Goudarzi1,*, Hamid Reza JamaatiHamid Reza Jamaati2, Gita EslamiGita Eslami1, Fatemeh FallahFatemeh Fallah1, Roxana KhanipourroshanRoxana Khanipourroshan3
1Infectious Diseases and Tropical Medicine Research Center, Shaheed Beheshti Medical University, Tehran, IR Iran
2National Research Institute of Tuberculosis and Lung Diseases, Shaheed Beheshti Medical University, Tehran, IR Iran
3Islamic Azad University, Tehran-North Unit


Archives of Clinical Infectious Diseases:Vol. 2, issue 1; 5-8
Article type:Research Article
How to Cite:Hossein GoudarziHamid Reza JamaatiGita EslamiFatemeh FallahRoxana KhanipourroshanUrinary Antigen Test EIA: A Valuable Rapid Clinical Method for the Ddiagnosis of Legionella.Arch Clin Infect Dis.2(1):5-8.

Abstract

Background:

Community acquired pneumonia (CAP) is a common health concern and the main mortality factor worldwide. Nowadays, legionella pneumophila is one of the most common microorganisms responsible for CAP. We designed this study to investigate the antigen test as a useful, simple and rapid test for early diagnosis of legionella pneumophila.

Materials and methods:

We enrolled 118 patients (32 females and 86 males) with CAP, COPD and asthma in Masih Daneshvari medical center during 2004 5. Clinical and microbiological evaluations were performed. Sputum culture and legionella urinary antigen tests were carried out.

Results:

Different types of bacteria were isolated from 118 patients. The most frequently isolated respiratory microorganisms were: streptococcus pneumonia (88%), candida spp. (76.2%), beta-hemolytic streptococcus (61.8%), neiseria spp (44.4%), staphylococcus (40.6%), klebsiella spp (27.1%), fungi (16.1%), E.coli (8.4%), and pseudomonas spp (5.1%). No legionella was detected from sputum specimens. Legionella urinary antigen testing was revealed to be positive in 3 males.

Conclusion:

Urinary antigen test is a particularly useful, simple and rapid test since it is often easier to obtain urine in ill patients. The results can be available within hours and it is also reliable enough to commence treatment.

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