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Archives of Clinical Infectious Diseases
This study was conducted to assess the prevalence of Hepatitis C virus (HCV), Hepatitis B virus (HBV) and Human immunodeficiency virus (HIV) among hemophilia and thalassemia patients.
Present study was conducted from October 2008 to December 2010 in Isfahan, Iran. One thousand one hundred and sixty adult multi-transfused patients (822 males, 338 females, mean age 22.711.5 years) suffering from beta-thalassemia (n = 545) and hemophilia (n=615) were enrolled in the study. Blood samples were obtained from the patients and were tested for HBs Ag, Anti-HCV Ag and Anti- HIV Ab. HCV positive patients underwent genotype determination.
Of 545 thalassemia patients, 312(57.2%) were male and 233 (42.8%) were female. From 615 hemophilia
HCV is the major virus of concern in multi-transfused patients. The strategies for prevention of HCV, HBV and HIV and safety of blood products in this respect have indeed been successful.
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