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Prevalence of Hepatitis C Virus, Hepatitis B virus, Human Immunodeficiency Virus and Related Risk Factors Among Hemophilia and Thalassemia Patients in Iran

Author(s):
Hamid KalantariHamid Kalantari1, Ahmad MirzabaghiAhmad Mirzabaghi2, Mojtaba AkbariMojtaba Akbari3, Zahra ShahshahanZahra Shahshahan4,*
1Associate Professor, Department of Gastroenterology, Isfahan Liver Disease research center, Isfahan, IR Iran
2Resident, Department of Internal Medicine
3Epidemiologist
4Associate Professor, Department of Obstetrics and Gynecology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, IR Iran.


Archives of Clinical Infectious Diseases:Vol. 6, issue 2
Article type:Research Article
How to Cite:Hamid KalantariAhmad MirzabaghiMojtaba AkbariZahra ShahshahanPrevalence of Hepatitis C Virus, Hepatitis B virus, Human Immunodeficiency Virus and Related Risk Factors Among Hemophilia and Thalassemia Patients in Iran.Arch Clin Infect Dis.6(2):null-null.

Abstract

Objectives:

This study was conducted to assess the prevalence of Hepatitis C virus (HCV), Hepatitis B virus (HBV) and Human immunodeficiency virus (HIV) among hemophilia and thalassemia patients.

Patients and Methods:

Present study was conducted from October 2008 to December 2010 in Isfahan, Iran. One thousand one hundred and sixty adult multi-transfused patients (822 males, 338 females, mean age 22.711.5 years) suffering from beta-thalassemia (n = 545) and hemophilia (n=615) were enrolled in the study. Blood samples were obtained from the patients and were tested for HBs Ag, Anti-HCV Ag and Anti- HIV Ab. HCV positive patients underwent genotype determination.

Results:

Of 545 thalassemia patients, 312(57.2%) were male and 233 (42.8%) were female. From 615 hemophilia

Conclusion:

HCV is the major virus of concern in multi-transfused patients. The strategies for prevention of HCV, HBV and HIV and safety of blood products in this respect have indeed been successful.

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