Effect of Short-Term Maximal Exercise on Biochemical Markers of Muscle Damage, Total Antioxidant Status, and Homocysteine Levels in Football Players

Authors

Omar Hammouda1,*, Hamdi Chtourou1, Anis Chaouachi1, Henda Chahed2, Salyma Ferchichi2, Choumous Kallel3, Karim Chamari4, Nizar Souissi4
1Research Laboratory 'Sport Performance Optimisation, National Center of Medicine and Science in Sport
2Laboratory of Biochemistry, CHU Farhat Hached, Sousse, Tunisia
3Laboratory of hematology, CHU Habib Bourguiba, Sfax, Tunisia
4High Institute of Sport and Physical Education, Ksar-Sad, Manouba University, Tunisia
*Corresponding Author: National Center of Medicine and Science in Sports (CNMSS), Bp263, Ave Med Ali Akid, 1004 El Menzah, Tunis, Tunisia., [email protected]. Email: [email protected]

Asian Journal of Sports Medicine:Vol. 3, issue 4; 239-246
Published online:Nov 30, 2012
Article type:Research Article
Received:Mar 20, 2012
Accepted:May 07, 2012
How to Cite:Hammouda O, Chtourou H, Chaouachi A, Chahed H, Ferchichi S, et al. Effect of Short-Term Maximal Exercise on Biochemical Markers of Muscle Damage, Total Antioxidant Status, and Homocysteine Levels in Football Players. Asian J Sports Med. 2012;3(4):34544. doi: https://doi.org/10.5812/asjsm.34544

Abstract

Purpose:

Prolonged physical exercise results in transient elevations of biochemical markers of muscular damage. This study examined the effect of short-term maximal exercise on these markers, homocysteine levels (Hcy), and total antioxidant status (TAS) in trained subjects.

Methods:

Eighteen male football players participated in this study. Blood samples were collected 5-min before and 3-min after a 30-s Wingate test.

Results:

The results indicated that plasma biochemical markers of muscle injury increased significantly after the Wingate test (P<0.05). Moreover, significant increase of white blood Cells and their main subpopulations (i.e. monocytes, neutrophiles, and lymphocytes) (P<0.001) has been observed. Likewise, uric acid, total bilirubin, and TAS increased significantly after exercise (P<0.05). However, Hcy levels were unaffected by the Wingate test (for 3-min post-exercise measurement).

Conclusions:

Short-term maximal exercise (e.g. 30-s Wingate test) is of sufficient intensity and duration to increase markers of muscle damage, and TAS; but not Hcy levels. Increases in the selected enzymes probably come primarily from muscle damage, rather than liver damage. Moreover, increase of TAS confirms the Wingate test induced oxidative stress.

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Copyright

© 2012, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.

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