article information

Asian Journal of Sports Medicine: Vol.3, issue 4; 239-246
published online: November 30, 2012
article type: Research Article
received: March 20, 2012
accepted: May 7, 2012
DOI: https://doi.org/10.5812/asjsm.34544
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Effect of Short-Term Maximal Exercise on Biochemical Markers of Muscle Damage, Total Antioxidant Status, and Homocysteine Levels in Football Players

authors:

avatar Omar Hammouda 1 , * , avatar Hamdi Chtourou 1 , avatar Anis Chaouachi 1 , avatar Henda Chahed 2 , avatar Salyma Ferchichi 2 , avatar Choumous Kallel 3 , avatar Karim Chamari 4 , avatar Nizar Souissi 4

Research Laboratory 'Sport Performance Optimisation, National Center of Medicine and Science in Sport
Laboratory of Biochemistry, CHU Farhat Hached, Sousse, Tunisia
Laboratory of hematology, CHU Habib Bourguiba, Sfax, Tunisia
High Institute of Sport and Physical Education, Ksar-Sad, Manouba University, Tunisia

how to cite: Hammouda O, Chtourou H, Chaouachi A, Chahed H, Ferchichi S, et al. Effect of Short-Term Maximal Exercise on Biochemical Markers of Muscle Damage, Total Antioxidant Status, and Homocysteine Levels in Football Players. Asian J Sports Med. 2012;3(4):34544. https://doi.org/10.5812/asjsm.34544.

Abstract

Purpose:

Prolonged physical exercise results in transient elevations of biochemical markers of muscular damage. This study examined the effect of short-term maximal exercise on these markers, homocysteine levels (Hcy), and total antioxidant status (TAS) in trained subjects.

Methods:

Eighteen male football players participated in this study. Blood samples were collected 5-min before and 3-min after a 30-s Wingate test.

Results:

The results indicated that plasma biochemical markers of muscle injury increased significantly after the Wingate test (P<0.05). Moreover, significant increase of white blood Cells and their main subpopulations (i.e. monocytes, neutrophiles, and lymphocytes) (P<0.001) has been observed. Likewise, uric acid, total bilirubin, and TAS increased significantly after exercise (P<0.05). However, Hcy levels were unaffected by the Wingate test (for 3-min post-exercise measurement).

Conclusions:

Short-term maximal exercise (e.g. 30-s Wingate test) is of sufficient intensity and duration to increase markers of muscle damage, and TAS; but not Hcy levels. Increases in the selected enzymes probably come primarily from muscle damage, rather than liver damage. Moreover, increase of TAS confirms the Wingate test induced oxidative stress.

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