Association of Anticardiolipin Antibodies and Extent of Coronary Artery Disease in Military Personnel and Non Military Population With Acute Coronary Syndrome

Bahareh  Hajibaratali; Shahram Baharvand; Shahrooz Yazdani

doi:10.21859/ijcp-010306

International Journal of Cardiovascular Practice

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https://doi.org/10.21859/ijcp-010306

Association of Anticardiolipin Antibodies and Extent of Coronary Artery Disease in Military Personnel and Non Military Population With Acute Coronary Syndrome

Author(s):

Bahareh Hajibaratali ^1,*,

Shahram Baharvand²,

Shahrooz Yazdani³

1Department of Cardiology, Labafinejad Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran

2Department of Rheumatolog, Aja University of Medical Sciences, Tehran, Iran

3Department of Cardiology, Shahid Rajaei Hospital Medical Center, Alborz University of Medical Sciences, Tehran, Iran

International Journal of Cardiovascular Practice:Vol. 1, issue 3; 57-61

Published online:Oct 30, 2016

Article type:Research Article

Received:Feb 19, 2016

Accepted:Aug 10, 2016

How to Cite:Bahareh Hajibaratali Shahram BaharvandShahrooz YazdaniAssociation of Anticardiolipin Antibodies and Extent of Coronary Artery Disease in Military Personnel and Non Military Population With Acute Coronary Syndrome.Int J Cardiovasc Pract.1(3):e130048.https://doi.org/10.21859/ijcp-010306.

Abstract

Introduction: Cardiac involvement is one of the chief complications considerably contributing to the morbidity and mortality of patients with systemic autoimmune diseases. Anticardiolipin antibody is a marker of elevated myocardial infarction risk and it also predicts post cardiac intervention risk. In the current study, we aimed to evaluate the association between anticardiolipin IgM and IgG levels and atherosclerotic involvement of coronary arteries.

Methods: Patients with acute coronary syndrome admitted to a military hospital were included in the study. Patients were categorized to military personnel and non-military personnel. Laboratory data including lipid profile, blood sugar, anticardiolipin IgM and anticardiolipin IgG were verified. Existence and the extent of Coronary Artery Disease (CAD) were defined according to angiographic findings. The relationship between anticardiolipin antibody levels and the number of vessels were evaluated.

Results: According to our sample population calculation, we performed the study on a total of 92 patients. Measurement of both anticardiolipin antibodies (IgM and IgG) in military personnel and non personnel patients showed no significant difference. In both military personnel and non personnel groups, there was a significant association between anticardiolipin IgM and IgG levels and number of coronary arteries with significant stenosis. The C Reactive Protein (CRP) level was significantly higher in military personnel.

Conclusions: According to the study results, anticardiolipin antibody levels were the same in both military personnel and non personnel. Also systolic and diastolic blood pressures were not significantly different in both groups. Increased CRP level in military personnel may be a warning signal about the possibility of premature CAD in this population, hence aggressive risk factor modification is recommended. Paradoxically lipid profile and FBS levels were more favorable in military personnel, which indirectly reflects their higher state of physical activity.

Keywords

Military Personnel

Angiography

Coronary Artery Disease

Antibodies Anticardiolipin

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Author(s):

Bahareh Hajibaratali :[PubMed][Scholar]
Shahram Baharvand:[PubMed][Scholar]
Shahrooz Yazdani:[PubMed][Scholar]