Thrombocytopenia as a Marker of Patient Outcome in Medical Intensive Care Unit

Abbas Fadaei; Seyed Mojtaba Heidari; Maryam Alizadeh Chamkhaleh; Mohammad Amin Abbasi

doi:10.21859/ijcp-03042

International Journal of Cardiovascular Practice

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https://doi.org/10.21859/ijcp-03042

Thrombocytopenia as a Marker of Patient Outcome in Medical Intensive Care Unit

Author(s):

Abbas Fadaei¹,

Seyed Mojtaba Heidari²,

Maryam Alizadeh Chamkhaleh³,

Mohammad Amin Abbasi^4,*

1Department of Pulmonology and Intensive Care Medicine, Shahid Labbafinejad Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran

2Department of Medicine, Shahid Labbafinejad Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran

3Student Research Committee, School of Medicine, Iran University of Medical Sciences, Tehran, Iran

4Department of Medicine, Clinical Research Development Unit, Firoozabadi Hospital, Iran University of Medical Sciences, Tehran, Iran

International Journal of Cardiovascular Practice:Vol. 3, issue 4; 70-73

Published online:Oct 01, 2018

Article type:Research Article

Received:May 20, 2018

Accepted:Jul 17, 2018

How to Cite:Fadaei A, Heidari SM, Alizadeh Chamkhaleh M, Abbasi MA. Thrombocytopenia as a Marker of Patient Outcome in Medical Intensive Care Unit. Int J Cardiovasc Pract. 2018;3(4):e130286. doi: https://doi.org/10.21859/ijcp-03042

Abstract

Introduction: Thrombocytopenia is a common hematologic disorder observed in many pathological conditions in critically ill patients. The current study aimed at investigating the prevalence of thrombocytopenia and its relationship with the length of stay and mortality among intensive care unit (ICU) patients.

Methods: The current prospective cohort study enrolled 150 patients consecutively admitted to the medical ICU during a nine-month period. Patients’ baseline characteristics and underlying diseases were recorded. Laboratory findings and admission mean platelets and platelet counts on the 3rd day of admission were obtained. Patients were divided into thrombocytopenic (platelet count of less than 150×109/L or decrease of platelet to more than 50%) and non-thrombocytopenic groups according to the 3rd day platelet count.

Results: Thrombocytopenia was detected in 53(35%) patients while 13 patients (8.6%) had severe thrombocytopenia (platelets count < 50 × 109/L). ICU stay and mortality were significantly higher in patients with thrombocytopenia compared with non-thrombocytopenic patients (16 ± 2.7 vs 12 ± 2.4 days, P = 0.01) and (45.5% vs 37.3%, P = 00.1) respectively.

Conclusions: Platelet might be considered as a prognosis monitor in ICU settings. Severe thrombocytopenia could be mentioned as a poor prognostic factor for increased mortality and prolonged hospitalization period in ICU patients

Keywords

Mortality

Prognosis

Thrombocytopenia

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Author(s):

Abbas Fadaei:[PubMed][Scholar]
Seyed Mojtaba Heidari:[PubMed][Scholar]
Maryam Alizadeh Chamkhaleh:[PubMed][Scholar]
Mohammad Amin Abbasi:[PubMed][Scholar]

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Thrombocytopenia as a Marker of Patient Outcome in Medical Intensive Care Unit

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