Thrombocytopenia as a Marker of Patient Outcome in Medical Intensive Care Unit

Abbas Fadaei; Seyed Mojtaba Heidari; Maryam Alizadeh Chamkhaleh; Mohammad Amin Abbasi

doi:10.21859/ijcp-03042

International Journal of Cardiovascular Practice

Current Issue All Issues In Press Accepted Manuscripts Search

Journal Information Editors & Boards Indexing and Listing Sources Journal Metrics Open Peer Review (OPR)Publication Ethics and Malpractice Statement Contact Us Support Reviewer and AE Registration Form

Authors Guide Submit Manuscript

https://doi.org/10.21859/ijcp-03042

Thrombocytopenia as a Marker of Patient Outcome in Medical Intensive Care Unit

Author(s):

Abbas Fadaei¹,

Seyed Mojtaba Heidari²,

Maryam Alizadeh Chamkhaleh³,

Mohammad Amin Abbasi^4,*

1Department of Pulmonology and Intensive Care Medicine, Shahid Labbafinejad Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran

2Department of Medicine, Shahid Labbafinejad Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran

3Student Research Committee, School of Medicine, Iran University of Medical Sciences, Tehran, Iran

4Department of Medicine, Clinical Research Development Unit, Firoozabadi Hospital, Iran University of Medical Sciences, Tehran, Iran

International Journal of Cardiovascular Practice:Vol. 3, issue 4; 70-73

Published online:Oct 01, 2018

Article type:Research Article

Received:May 20, 2018

Accepted:Jul 17, 2018

How to Cite:Abbas FadaeiSeyed Mojtaba HeidariMaryam Alizadeh ChamkhalehMohammad Amin AbbasiThrombocytopenia as a Marker of Patient Outcome in Medical Intensive Care Unit.Int J Cardiovasc Pract.3(4):e130286.https://doi.org/10.21859/ijcp-03042.

Abstract

Introduction: Thrombocytopenia is a common hematologic disorder observed in many pathological conditions in critically ill patients. The current study aimed at investigating the prevalence of thrombocytopenia and its relationship with the length of stay and mortality among intensive care unit (ICU) patients.

Methods: The current prospective cohort study enrolled 150 patients consecutively admitted to the medical ICU during a nine-month period. Patients’ baseline characteristics and underlying diseases were recorded. Laboratory findings and admission mean platelets and platelet counts on the 3rd day of admission were obtained. Patients were divided into thrombocytopenic (platelet count of less than 150×109/L or decrease of platelet to more than 50%) and non-thrombocytopenic groups according to the 3rd day platelet count.

Results: Thrombocytopenia was detected in 53(35%) patients while 13 patients (8.6%) had severe thrombocytopenia (platelets count < 50 × 109/L). ICU stay and mortality were significantly higher in patients with thrombocytopenia compared with non-thrombocytopenic patients (16 ± 2.7 vs 12 ± 2.4 days, P = 0.01) and (45.5% vs 37.3%, P = 00.1) respectively.

Conclusions: Platelet might be considered as a prognosis monitor in ICU settings. Severe thrombocytopenia could be mentioned as a poor prognostic factor for increased mortality and prolonged hospitalization period in ICU patients

Keywords

Mortality

Prognosis

Thrombocytopenia

Fulltext

Full-text is available in PDF file.

comments

Crossmark

Checking

Share on

Comments

Number of Comments:0

Cited by

CrossRef 0

Metrics

Get Permission (article level)

Purchasing Reprints

Copyright Clearance Center (CCC) handles bulk orders for article reprints for Brieflands. To place an order for reprints, please click here ( https://www.copyright.com/landing/reprintsinquiryform/ ). Clicking this link will bring you to a CCC request form where you can provide the details of your order. Once complete, please click the ‘Submit Request’ button and CCC’s Reprints Services team will generate a quote for your review.

Search Relations

Author(s):

Abbas Fadaei:[PubMed][Scholar]
Seyed Mojtaba Heidari:[PubMed][Scholar]
Maryam Alizadeh Chamkhaleh:[PubMed][Scholar]
Mohammad Amin Abbasi:[PubMed][Scholar]