Effect of Retrograde Autologous Priming on Clinical Outcome of Cardiopulmonary Bypassing on Patients Undergoing Coronary Artery bypass Grafting

Musa  Rafiee; Mohammad Zia Toutounchi; Rezvan Yazdani Soodejani; Nooredin Mohamadi

doi:10.29252/ijcp-26691

International Journal of Cardiovascular Practice

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https://doi.org/10.29252/ijcp-26691

Effect of Retrograde Autologous Priming on Clinical Outcome of Cardiopulmonary Bypassing on Patients Undergoing Coronary Artery bypass Grafting

Author(s):

Musa Rafiee ¹,

Mohammad Zia Toutounchi²,

Rezvan Yazdani Soodejani³,

Nooredin Mohamadi^1,*

1Department of Critical Care Nursing, Center for Nursing Care Research, Nursing and Midwifery Faculty, Iran University of Medical Sciences, Tehran, Iran

2Heart Valve Disease Research Center, Rajaie Cardiovascular Medical & Research Center, Iran University of Medical Sciences, Tehran, Iran

3Department of Nursing, School of Nursing and Midwifery, Shahrekord University of Medical Sciences, Shahrekord, Iran

International Journal of Cardiovascular Practice:Vol. 4, issue 4; 117-122

Published online:Dec 05, 2019

Article type:Research Article

Received:Aug 10, 2019

Accepted:Nov 05, 2019

How to Cite:Musa Rafiee Mohammad Zia ToutounchiRezvan Yazdani SoodejaniNooredin MohamadiEffect of Retrograde Autologous Priming on Clinical Outcome of Cardiopulmonary Bypassing on Patients Undergoing Coronary Artery bypass Grafting.Int J Cardiovasc Pract.4(4):e130569.https://doi.org/10.29252/ijcp-26691.

Abstract

Introduction: Cardiopulmonary bypass is a standard and low mortality-associated method used across the world. This method allows cardiac surgery to be performed in a bloodless environment. The study aimed to compare Conventional priming and Retrograde autologous prime (RAP) on patients undergoing coronary artery bypass grafting (CABG).

Methods: The study population was patients undergoing CABG using cardiopulmonary bypass in Rajaei Hospital, of whom 80 patients were selected by simple random sampling convenience sampling and then were randomly assigned to two groups: Conventional priming and RAP. Demographic information, blood components transfused in the operating room and the intensive care unit, ejection fraction (EF) of left ventricle and changes in blood gases were collect.

Results: The mean requirement for red blood cell transfusion bags to the patient during surgery was lower in the RAP group than the conventional priming group (P = 0.002). But the difference after surgery in both groups was not significant statistically (P = 0.2). The difference amount of platelet transfusion during operation the difference was not statistically significant (P = 0.4). The difference postoperative platelet transfusion was not statistically significant (P = 0.7). The fresh frozen plasma transfusion during surgery in the RAP group lower than the usual prime group, but the difference was not statistically significant (P = 0.406). The Fresh frozen plasma (FFP) transfusion after surgery in the two groups was not statistically significant (P = 0.217).

Conclusion: RAP is compared with conventional priming a safe and low-cost technique in reducing the priming volume of the CPB system, causes less hemodilution, and reduces the need for intra- and postoperative blood transfusion. Therefore, it is recommended to consider RAP as an effective and low-cost technique of priming Cardiopulmonary bypass circuits.

Keywords

Blood Transfusion

Autologous

Cardiopulmonary Bypass

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Author(s):

Musa Rafiee :[PubMed][Scholar]
Mohammad Zia Toutounchi:[PubMed][Scholar]
Rezvan Yazdani Soodejani:[PubMed][Scholar]
Nooredin Mohamadi:[PubMed][Scholar]