Effects of a calcium supplement on serum lipoproteins, apolipoprotein B, and blood pressure in overweight men

Farzad Shidfar; Melika Moghayedi; Scott Reza Jafarian Kerman; Sharieh Hosseini; Shahrzad Shidfar

International Journal of Endocrinology and Metabolism

Research Institute for Endocrine Sciences

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Effects of a calcium supplement on serum lipoproteins, apolipoprotein B, and blood pressure in overweight men

Author(s):

Farzad Shidfar^1,*,

Melika Moghayedi¹,

Scott Reza Jafarian Kerman²,

Sharieh Hosseini³,

Shahrzad Shidfar⁴

1School of Health, Tehran University of Medical Sciences, Tehran, IR Iran

2Scientific Student’s Research Committee, Tehran University of Medical Sciences, Tehran, IR Iran

3Islamic Azad University, Sari branch, Sari, IR Iran

4University of Massachusetts, Memorial Hospital, Worcester, Massachusetts, USA

International Journal of Endocrinology and Metabolism:Vol. 8, issue 4; 194-200

Published online:Oct 31, 2010

Article type:Research Article

Received:Aug 22, 2010

Accepted:Jan 01, 2011

How to Cite:Farzad ShidfarMelika MoghayediScott Reza Jafarian KermanSharieh HosseiniShahrzad ShidfarEffects of a calcium supplement on serum lipoproteins, apolipoprotein B, and blood pressure in overweight men.Int J Endocrinol Metab.8(4):194-200.

Abstract

Calcium Lipoproteins Apolipoprotein B Blood pressure Overweight Background: Calcium supplements can improve hypertension, hyperlipidemia, and regulation of body weight in overweight persons. Objectives: The aim of the study was to assess the effect of calcium supplementation on blood pressure and serum lipid profile. Materials and Methods: 49 overweight men (age range = 34.4 ± 4.8, BMI = 27.5 ± 1.7) were given a placebo or carbonate calcium (1,250 mg elemental calcium) daily for 8 weeks in a randomized, double-blind clinical trial. Serum lipids and blood pressure were measured before and after the trial. A 24-hour dietary recall questionnaire was completed for each person at baseline, in the 4th week, and at the end of the study. Results: There were no significant differences in weight, serum triglycerides, and HDL-c between the experimental and control groups at the end of the study, but there were significant differences in the mean changes of total cholesterol (12.9 versus 1%, P < .001), LDL-c (8.5 versus 1.6%, P = .003), and apolipoprotein B (7.2 vs. 0.18%, P = .044) in the experimental versus control groups at the end of the study. Additionally, in the experimental group, mean changes of systolic blood pressure had reduced significantly compared to the placebo group (6.84 vs. 3.05%, P = .046). Conclusions: The results suggest that calcium supplements may have a favorable effect on reducing cardiovascular risk in overweight men.

Implication for health policy/practice/research/medical education:
This article has implication for health policy, research and medical education because the mortality due to cardiovascular disease is increasing, on the other hand we have low calcium intake in our society and this article can be a good aricle for Health policy, research and medical education.

Please cite this paper as:
Shidfar F , Moghayedi M , Jafarian Kerman SR, Hosseini S, Shidfar S. Effects of a calcium supplement on serum lipoproteins, apolipoprotein B, and blood pressure in overweight men. Int J Endocriol Metab. 2010;8(4):194-200.

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