The Respiratory Exchange Ratio Is Higher in Older Subjects, but Is Reduced by Aerobic Exercise Training

51, Departments of Physiology and Biophysics University at Buffalo, Buffalo, USA. 2, Centers for Research and Education in Special Environments, University at Buffalo, dpenderg@buffalo.edu, USA

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International Journal of Endocrinology and Metabolism:Vol. 9, issue 1; 264-270

Published online:Jan 01, 2011

Article type:Research Article

Received:Nov 05, 2010

Accepted:Dec 30, 2010

How to Cite:Atcharaporn LimprasertkulNadine M. FisherNadine M FisherAtif B. AwadAtif B AwadDavid R. PendergastDavid R Pendergastet al.The Respiratory Exchange Ratio Is Higher in Older Subjects, but Is Reduced by Aerobic Exercise Training.Int J Endocrinol Metab.9(1):264-270.https://doi.org/10.5812/kowsar.1726913X.1789.

Abstract

Background: Previous studies have suggested reduced fat metabolism in older subjects. However, corrections for their reduced maximal oxygen consumption and the effects of training and substrate availability have not been fully examined.
Objectives: Fat metabolism (FM) in older subjects (n = 14, 75 ± 7 yrs), and the effects of exercise training were compared with FM in younger subjects (n = 16, 22 ± 3 yrs).
Materials and Methods: All subjects completed a maximal exercise test and a sustained submaximal run at 70% of their maximal capacity. The respiratory exchange ratio (RER) and blood substrate levels were determined. Older subjects were re-tested after training.
Results: Young subjects had higher oxygen consumption (VO2) peak (36.3 ± 6.7 vs. 23.7 ± 6.2 ml/kg/min) and lower slope of RER vs. VO2 than older subjects. However, the slope of the RER vs. VO2 relationship was not different between younger and older subjects, after correction for their VO2 peaks. Younger subjects had longer sustained exercise times (45.5 ± 17.6 min) than the elderly (30.2 ± 14.0 min), pre-training. Post-training, there was a significant increase in VO2 peak (25%) in older subjects (P = 0.001) and submaximal exercise time (30.2 ± 14.0 vs. 58.3 ± 27.3min, P = 0.020). Respiratory exchange ratio was reduced during both exercises after training (0.90 ± 0.03 vs. 1.00 ± 0.03, P = 0.04).
Conclusions: The RER of older subjects was not different from that of younger subjects, after correction for the VO2 peak. The VO2 peak, sustained exercise time, and RER decreased after training in older subjects, indicating increased fat metabolism.

Implication for health policy/practice/research/medical education:
The present study demonstrates the importance of maximal oxygen consumption in determining fat metabolism in the elderly. When this is considered along with the other reported benefits of relatively high maximal oxygen consumption in the elderly emphasizes the importance of regular physical activity to health and wellness.

Please cite this paper as:
Limprasertkul A, Fisher NM, Awad AB, Pendergast DR. The Respiratory Exchange Ratio Is Higher in Older Subjects, but Is Reduced by Aerobic Exercise Training. Int J Endocriol Metab. 2011;9(1):264-70.DOI:10.5812/kowsar.1726913X.1789

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Author(s):

Atcharaporn Limprasertkul:[PubMed][Scholar]
Nadine Fisher:[PubMed][Scholar]
Nadine Fisher:[PubMed][Scholar]
Atif Awad:[PubMed][Scholar]
Atif Awad:[PubMed][Scholar]
David Pendergast:[PubMed][Scholar]
David Pendergast:[PubMed][Scholar]