Logo

Relation Between Pre-and Post-Dexamethasone Test Cortisol Values in Cushing's Disease

Author(s):
Laurberg PLaurberg Pe,*


International Journal of Endocrinology and Metabolism:Vol. 2, issue 2; 74-77
Published online:Jan 01, 2004
Article type:Research Article
How to Cite:Laurberg PRelation Between Pre-and Post-Dexamethasone Test Cortisol Values in Cushing's Disease.Int J Endocrinol Metab.2(2):74-77.

Abstract

Introduction:

The dexamethasone test has been widely used for diagnosing hypercortisolism.

Materials and Methods:

We assessed the relationship between the basal and suppressed cortisol values in urine and plasma during a low-dose dexamethasone test in patients with proved Cushing's disease.

Results:

A statistically highly significant correlation was found (for urine cortisol: r = 0.66, P

Conclusions:

These findings imply that the lower the pretest cortisol values, the lower are the suppressed values. In patients with suspected Cushing's syndrome and only slightly elevated cortisol excretjon or low plasma concentration, the outcome might easily be considered normal. This point is particularly pertinent when assessing the post-treatment status.

Full Text

Full text is available in PDF

comments

Leave a comment here

Share on
Metrics

Purchasing Reprints

  • Copyright Clearance Center (CCC) handles bulk orders for article reprints for Brieflands. To place an order for reprints, please click here (   https://www.copyright.com/landing/reprintsinquiryform/ ). Clicking this link will bring you to a CCC request form where you can provide the details of your order. Once complete, please click the ‘Submit Request’ button and CCC’s Reprints Services team will generate a quote for your review.