Abstract
This research aimed at investigating the correla-tion between postprandial dyslipidemia and ca-rotid intimae-media thickness in people with dia-betes. Materials and Methods: In 28 diabetic patients and 22 age and sex- matched healthy adults, the carotid intimae-media thickness was measured using Doppler ultrasound. Blood glucose, total cholesterol, triglycerides, LDL and HLD choles-terol level were measured after overnight fasting and again 4 hours after a standard high-fat meal. Results: The carotid intimae-media thickness of diabetic patients was greater than normal sub-jects (0.96±0.29 mm vs. 0.75±0.17 mm, respec-tively p=0.008). Diabetic patients showed post-prandial hypertriglyceridemia (P=0.03). In pa-tients with fasting hyperglycemia and postpran-dial hypertriglyceridemia, carotid intimae-media thickness was greater than in patients with nor-mal levels (p=0.04 and p=0.03 respectively). Conclusion: Postprandial hypertriglyceridemia and fasting hyperglycemia may be an independ-ent risk factor for early atherosclerosis and macrovascular disease in individuals with type 2 diabetes.
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