Retrospective Analysis of a Long Term Iodine Intervention Program in Rural Iran


avatar N Salarkia 1 , * , avatar M Hedayati 2 , avatar F Azizi 2

National Nutrition and Food Technology Research Institute,, IR.Iran
Endocrine Research Center,Shaheed Beheshti Medical University, IR.Iran

how to cite: Salarkia N, Hedayati M, Azizi F. Retrospective Analysis of a Long Term Iodine Intervention Program in Rural Iran. Int J Endocrinol Metab. 2007;5(1): 16-25. 


This investigation aimed at evaluating the effect of iodine supplementation on the IDD impact indicators in a group of 571 hypothyroid iodine deficient schoolchildren. Materials and Methods: Values of levels obtained were compared with data from our previous 1989 study in these villages and results of the comparison showed that total goiter rate decreased by 42% in 1999. Results: A significant decrease in grade 2 goiter concomitant with an increase in grade 1 goiter was seen, P<0.001. Serum T4, T3, TSH concentrations, urinary iodine level and IQ were normal in all children. Mean IQ was higher in children aged 6-10 years as compared to other age groups, P<0.05. Conclusion: Study shows that euthyroidism induced by administration of iodized oil in hypothyroid iodine deficient schoolchildren can be maintained following iodized salt consumption.

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