Assessment of Antioxidant Vitamins Retinol and ?- Tocopherol in Plasma and Ascorbic Acid in Plasma and Mononuclear Leukocytes in Type 2 Diabetics

Authors

M Firoozrai1,*, I Nourmohammadi2, K Khanaki2
1Department of Biochemistry, College of Medicine, Iran University of Medical Sciences, [email protected], I.R.Iran
2Department of Biochemistry, College of Medicine, Iran University of Medical Sciences, I.R.Iran
*Corresponding Author: Department of Biochemistry, College of Medicine, Iran University of Medical Sciences, [email protected], I.R.Iran. Email: [email protected]

International Journal of Endocrinology and Metabolism:Vol. 4, issue 4; 202-205
Published online:Oct 31, 2006
Article type:Research Article
Received:Jan 09, 2005
Accepted:Nov 26, 2005
How to Cite:Firoozrai M, Nourmohammadi I, Khanaki K. Assessment of Antioxidant Vitamins Retinol and ?- Tocopherol in Plasma and Ascorbic Acid in Plasma and Mononuclear Leukocytes in Type 2 Diabetics. Int J Endocrinol Metab. 2006;4(4):. doi:

Abstract

The rise and along with this increase there is a growing interest in the efficacy of antioxidant vitamin therapy in the treatment of this malady.

Materials and Methods: In this case-control study, the levels of antioxidant vitamins retinol, -tocopherol and ascorbic acid were measured with HPLC and colorimetric method, in plasma and mononuclear leukocytes of patients with diagnosed Type 2 diabetes(n=62).

Results: We observed significantly lower ascorbicacid levels in mononuclear leukocytes in our study group when compared to controls.

Conclusion: While these results are not definitive, we believe they do indicate that further studies are needed to include a larger segment of the population and an evaluation of dietary intakes and habits.

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© 2006, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.

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