Assessment of Antioxidant Vitamins Retinol and ?- Tocopherol in Plasma and Ascorbic Acid in Plasma and Mononuclear Leukocytes in Type 2 Diabetics

authors:

avatar M Firoozrai 1 , * , avatar I Nourmohammadi 2 , avatar K Khanaki 2

Department of Biochemistry, College of Medicine, Iran University of Medical Sciences, mfiroozrai@yahoo.com, I.R.Iran
Department of Biochemistry, College of Medicine, Iran University of Medical Sciences, I.R.Iran
International Journal of Endocrinology and Metabolism: Vol.4, issue 4; 202-205
article type: Original Article
received: January 9, 2005
accepted: November 26, 2005

How To Cite Firoozrai M, Nourmohammadi I, Khanaki K. Assessment of Antioxidant Vitamins Retinol and ?- Tocopherol in Plasma and Ascorbic Acid in Plasma and Mononuclear Leukocytes in Type 2 Diabetics. Int J Endocrinol Metab. 2006;4(4): 202-205. 

Abstract

The rise and along with this increase there is a growing interest in the efficacy of antioxidant vitamin therapy in the treatment of this malady.

Materials and Methods: In this case-control study, the levels of antioxidant vitamins retinol, -tocopherol and ascorbic acid were measured with HPLC and colorimetric method, in plasma and mononuclear leukocytes of patients with diagnosed Type 2 diabetes(n=62).

Results: We observed significantly lower ascorbicacid levels in mononuclear leukocytes in our study group when compared to controls.

Conclusion: While these results are not definitive, we believe they do indicate that further studies are needed to include a larger segment of the population and an evaluation of dietary intakes and habits.

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