Abstract
The pathogenesis and the treatment of Graves’ Ophthalmopathy (GO), the most common extrathyroidal mani
festation of Graves’ disease, are still debated [reviewed in1]. Although associated with Graves’ hyperthyroidism in most patients, GO may also occur with euthyroidism or hypothyroidism from Hashimoto’s thyroiditis (“euthyroid Graves’ disease”). GO precedes, occurs simultaneously with or follows hyperthyroidism in 13%, 43% and 44% of patients, respectively.2 The time interval between the beginning of GO and the onset of hyperthyroidism is <18 months in 85% of patients.
festation of Graves’ disease, are still debated [reviewed in1]. Although associated with Graves’ hyperthyroidism in most patients, GO may also occur with euthyroidism or hypothyroidism from Hashimoto’s thyroiditis (“euthyroid Graves’ disease”). GO precedes, occurs simultaneously with or follows hyperthyroidism in 13%, 43% and 44% of patients, respectively.2 The time interval between the beginning of GO and the onset of hyperthyroidism is <18 months in 85% of patients.
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Copyright
© 2006, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.