Transfusion-Associated HIV Infection in Pediatric Leukemia Patients (Two Case Reports)

Shilong Yang; Yongmin Tang; Hua Song; Mingming Zhou; Xuejun Chen; Botao Ning

IJ Pediatrics

The Scientific Journal of Growth & Development Research Center

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Transfusion-Associated HIV Infection in Pediatric Leukemia Patients (Two Case Reports)

Author(s):

Shilong Yang¹,

Yongmin Tang¹,

Hua Song¹,

Mingming Zhou²,

Xuejun Chen²,

Botao Ning^1,*

1Division of Hematology-Oncology, Children's Hospital, Zhejiang University School of Medicine, China

2Division of Clinical Laboratory, Children's Hospital, Zhejiang University School of Medicine, Zhejiang, China

IJ Pediatrics:Vol. 22, issue 3; 412-416

Published online:Sep 30, 2012

Article type:Case Report

Received:Dec 03, 2010

Accepted:Nov 20, 2011

How to Cite:Shilong YangYongmin TangHua SongMingming ZhouXuejun ChenBotao Ninget al.Transfusion-Associated HIV Infection in Pediatric Leukemia Patients (Two Case Reports).Iran J Pediatr.22(3):412-416.

Abstract

Background: Background: Congenital insensitivity to pain with anhidrosis (CIPA) is characterized by recurrent episodes of infections and unexplained fever, anhidrosis (inability to sweat), and absence of reaction to noxious stimuli, self-mutilating behavior, mental retardation and damages to oral structures.
Case Presentation: In this article, we have demonstrated the signs and symptoms of 4 children that refer to the pediatrics department of the Imam Khomeini hospital and assay about their complications with this disease. They mostly presented by recurrent osteomyelitis in their feet that severely controlled by antibiotic therapy and even surgery. They had no pain sensation in spite of deep sore and infection.
Conclusion: This syndrome can be diagnosed by clinical and paraclinical tests together but it would be better to confirm by genetic test. The diagnosis of this syndrome helps us to try for the better quality of life for the patients and avoid unnecessary amputations.

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