Transfusion-Associated HIV Infection in Pediatric Leukemia Patients (Two Case Reports)

authors:

avatar Shilong Yang 1 , avatar Yongmin Tang 1 , avatar Hua Song 1 , avatar Mingming Zhou 2 , avatar Xuejun Chen 2 , avatar Botao Ning 1 , *

Division of Hematology-Oncology, Children's Hospital, Zhejiang University School of Medicine, China
Division of Clinical Laboratory, Children's Hospital, Zhejiang University School of Medicine, Zhejiang, China
Iranian Journal of Pediatrics: Vol.22, issue 3; 412-416
published online: September 30, 2012
article type: Case Report
received: December 03, 2010
accepted: November 20, 2011

How To Cite Yang S, Tang Y, Song H, Zhou M, Chen X, et al. Transfusion-Associated HIV Infection in Pediatric Leukemia Patients (Two Case Reports). Iran J Pediatr. 2012;22(3): 412-416. 

Abstract

Background: Background: Congenital insensitivity to pain with anhidrosis (CIPA) is characterized by recurrent episodes of infections and unexplained fever, anhidrosis (inability to sweat), and absence of reaction to noxious stimuli, self-mutilating behavior, mental retardation and damages to oral structures.
Case Presentation: In this article, we have demonstrated the signs and symptoms of 4 children that refer to the pediatrics department of the Imam Khomeini hospital and assay about their complications with this disease. They mostly presented by recurrent osteomyelitis in their feet that severely controlled by antibiotic therapy and even surgery. They had no pain sensation in spite of deep sore and infection.
Conclusion: This syndrome can be diagnosed by clinical and paraclinical tests together but it would be better to confirm by genetic test. The diagnosis of this syndrome helps us to try for the better quality of life for the patients and avoid unnecessary amputations.
 

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