Epicardial Adiposity in Children with Obesity and Metabolic Syndrome

authors:

avatar Erdal Eren 1 , * , avatar Bulent Koca 2 , avatar Mehmet Ture 3 , avatar Bulent Guzel 4

Iranian Journal of Pediatrics: Vol.24, issue 4; 411-417
published online: July 06, 2014
article type: Research Article
received: August 06, 2013
accepted: June 06, 2014

how to cite: Eren E , Koca B , Ture M , Guzel B . Epicardial Adiposity in Children with Obesity and Metabolic Syndrome. Iran J Pediatr. 2014;24(4): 411-417. 

Abstract

Objective: Obesity increases cardiac diseases by increasing tendency to atherosclerosis. Our aim was to define epicardial adipose tissue thickness, and its related factors in obese children.Methods: Total of 94 patients were divided into obesity with metabolic syndrome (MS) (n=30), obesity without MS (n=33), and control (n=31) groups. Auxological values with fasting glucose, fasting insulin, alanine transaminase, serum lipid levels, and high sensitive C-reactive protein levels were evaluated. Epicardial adipose tissue thickness, interventricular septum thickness and left ventricular mass were measured by echocardiography.Findings: Weight, body mass index, waist circumference, insulin, alanine transaminase, and high sensitive C-reactive protein values were markedly higher in obesity group when compared with controls (P<0.001). Epicardial adipose tissue thickness was 0.64±0.23 cm in obesity with MS; 0.60±0.20 cm in obesity without MS, and 0.27±0.12 cm in control group (P<0.001). Interventricular septum thickness and left ventricular mass values were markedly high in obesity without MS group (P<0.001 and P=0.002).Conclusion: Our study has indicated that obesity has unfavorable effects on heart starting in the adolescence.
 

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