The Efficacy of Intermittent Walking in Water on the Rate of MHPG sulfate and the severity of depression

authors:

avatar Valiollah Dabidy Roshan 1 , * , avatar Mehdi Pourasghar 2 , avatar Zeinab Mohammadian 3

Associate Professor of Physical Education and Sport Sciences, Department of sport Physiology, University of Mazandaran, Babolsar, Iran
Psychiatry and Behavioral Sciences Research Center , Mazandaran University of Medical Sciences, Sari, Iran
College of Physical Education and Sport Sciences, Department of sport Physiology, University of Mazandaran, Babolsar, Iran
Iranian Journal of Psychiatry and Behavioral Sciences: Vol.5, issue 2; 26-31
published online: September 02, 2011
article type: Original Article
received: November 06, 2010
revised: July 08, 2011
accepted: April 10, 2011

how to cite: Dabidy Roshan V, Pourasghar M, Mohammadian Z. The Efficacy of Intermittent Walking in Water on the Rate of MHPG sulfate and the severity of depression. Iran J Psychiatry Behav Sci. 2011;5(2): 26-31. 

Abstract

Objective: Many studies evaluated the efficacy of exercise on some depression indices, but the effect of physical exercise in exhilarating milieu on urine 3-Methoxy-4-Hydroxyphenylglycol (MHPG) sulfate-the main metabolite of norepinephrine is not clear. The purpose of this research was to study the effect of a six-week intermittent walking in the water on 24-hour urine MHPG sulfate in depressed female teenagers.
Methods: Twenty-four high school female students with depression were divided randomly into case and control group. Pool walking exercise program was implemented 3 sessions weekly for 6 weeks and with a rate of 60-70% of the maximum heart rate. The control group didnít enter any exercise protocol and did not receive any other anti-depressant therapy. HPLC-fluorometric detection assay was used to measure 24-hour urine MHPG sulfate values. The data was analyzed with t-test and Piersonís correlation tests.
Results: Twenty hour urine MHPG sulfate increased from 1.93 (±0.59) to 4.66 (±0.85) micromole in case group (P ≤ 0.001), and in control group from 1.67 (±0.58) to 1.80 (±0.58) micromole. Increase of 24-hour urine MHPG sulfate and increasing of maximum oxygen consumption showed significant positive correlation (r = 0.65), and a significant negative correlation (r = 0.65) was observed between urine MHPG sulfate and Hamilton Rating Scale for Depression (Ham-D) score.
Conclusion: Aerobics training in exhilarating environments shows desirable influence over reduction of depression. This reduction of depression is correlated with MHPG sulfate elevation.
Declaration of Interest: None.
Clinical Trial Registration: URL: #_> http://www.Irct.ir/Unique identifier: IRCT201104251457N8
Citation: Dabidy Roshan V, Pourasghar M, Mohammadian Z. The efficacy of intermittent walking in water on the rate of MHPG sulfate and the severity of depression.. Iran J Psychiatry Behav Sci 2011; 5(2): 26-31.

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