IJ Radiology
To investigate the effect of noise and denoising on the measurement of magnetic resonance (MR) imaging T2* values at interventricular septum of the heart in thalassemia major patients. A second objective is to estimate the T2* value based on the improvement of signal to noise ratio (SNR).
Different levels of Rician and Gaussian noises were added to the cardiac T2* MR images of 20 thalassemia major patients. The state-of-art denoising methods were applied to the obtained noisy images. T2* values of the interventricular septum and SNR were measured in both series of images by Segment and Matlab software, respectively.
With respect to the Gaussian noisy and denoised images in different noise levels, although SNR improved, there were no significant differences between T2* values in original, noisy and denoised images. On the other hand, after denoising images with Rician noise a relation between improvement of SNR and T2* value is noticed. A predictor model is constructed based on the level of Rician noise for each method.
In the case of existence Gaussian noise, the results confirm that denoising is not effective on the measurement of T2* value. In the case of image distortion by Rician noise, a predictor model is proposed to estimate the original T2* value. The predictor model is used to estimate the T2* value of new patients. The predicted T2* values were in good agreement with the corresponding original T2* values.
© 2017, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.
Gholami Bardeji S, Gholami Z, Jalli R, Lotfi M, Karimi M, et al. On the Selection of Region of Interest in Measurement of Cardiac Magnetic Resonance Imaging T2* Value in Thalassemia Major Patients. I J Radiol. 2017;14(Special Issue):e48013. doi: https://doi.org/10.5812/iranjradiol.48013
Mohammadi S, Jalilian M, Absalan F, Maghsoudi F, Samimi Z. Investigating the Relationship Between Liver and Heart Iron Overload Measured by T2 ⃰ Magnetic Resonance Imaging with Serum Ferritin Level, Liver Enzyme Ratio (Aspartate Aminotransferase / Alanine Aminotransferase) and Electrocardiography Findings in Patients with Thalassemia Major. Compr Health Biomed Stud. 2024;2(4):e151439. doi: https://doi.org/10.5812/chbs-151439
Lotfi M, Rouhezamin MR, Bijan B, Sefidbakht S, Karimi M, et al. Water Only Sequence: An Accurate Method to Estimate Hepatic Siderosis in Patients with Thalassemia Major and Intermedia. I J Radiol. 2020;17(2):e96811. doi: https://doi.org/10.5812/iranjradiol.96811
Ghandi Y, Habibi D, Eghbali A. Assessment of the Relationship Between Iron Overload Based on Cardiac T2* MRI and Fragmented QRS in Beta-Thalassemia Major Patients. Shiraz E-Med J. 2020;21(8):e96612. doi: https://doi.org/10.5812/semj.96612
Bornaun H, Dedeoglu R, Oztarhan K, Dedeoglu S, Erfidan E, et al. Detection of Early Right Ventricular Dysfunction in Young Patients With Thalassemia Major Using Tissue Doppler Imaging. Inn J Pediatr. 2016;26(3):e5808. doi: https://doi.org/10.5812/ijp.5808
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